My fave postdoc project is out today!! This manuscript has been a labor of love and I'm so excited to finally share it with the broader immunology community.
science.org/doi/10.1126/sc…

Intracellular peptide-targeting CARs and harnessing microbes to 'paint' tumors - creative engineering at its best! Excited to see what new CAR-T approaches are on the horizon. ASH Mark Yarmarkovich Tal Danino

ashpublications.org/thehematologis…

Fred Hutch’s Albert C. Yeh, MD presents “Microbiota-Specific T Cells Contribute to Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation” at #ASH23 #gvhd 👉 ash.confex.com/ash/2023/webpr…

CONGRESS | #ASH23 | Albert C. Yeh, MD Fred Hutchinson Cancer Center discusses the influence of microbiota-specific T-cells on GvHD after allo-HSCT, concluding that donor T-cells for microbial antigen present in the recipient promote GvHD lethality and the allo-response increases the presence of microbial

Does post-ASCT G-CSF truly benefit patients, or just make their labs look better? We took a deep dive into our data at Fred Hutchinson Cancer Center/UW Medicine to learn more. Thank you, Albert C. Yeh, MD, for your outstanding mentorship. | Transplantation and Cellular Therapy Journal astctjournal.org/article/S2666-…

Thank you ASTCT for supporting us aspiring investigators Fred Hutchinson Cancer Center !

Huge thank you to Aaron Ring for being an amazing collaborator on all of the DR-18 (engineered IL-18) work!

1/6 Can #AlphaFold learn from + & - labeled data to predict peptide binding better? w/ Phil Bradley Justas Dauparas Minkyung Baek Mohamad Abedi David Baker we present joint structure prediction-classification fine-tuning of #AF2 to classify pMHC binding.Institute for Protein Design Fred Hutchinson Cancer Center

And it’s out!! science.org/doi/10.1126/sc…
Ever wonder what happens when patients stop responding to novel therapies? Here Chapuis Lab Fred Hutchinson Cancer Center we have been working to find out why. Our paper reveals a mechanism of immune escape in an unusual patient case.
🧵👇 1/14

Fred Hutch is looking for a director of the Fred Hutch Innovation Lab (FHIL). The lab is evaluating, developing, and applying the next generation of genomics and cellular analysis technologies.

Take a look at this opportunity to join us in Seattle!

careers-fhcrc.icims.com/jobs/21256/dir…

After 2 years of collaborative work with Vanderbilt Health and @QIMRBerghofer we are excited to share our article on long-term immunologic effects of CMV exposure in bone marrow transplant. Thank you all! Hill Lab
authors.elsevier.com/a/1eKmT1UYwbmUj

Excited to be presenting our work at #ASH21 later today, titled “Non-Genetic Determinants of Clonotypic T Cell Expansion Following Allogeneic Stem Cell Transplant” from the Hill Lab!

Our lab is hiring! We are looking for a technician and a research project manager to join our efforts in human immune profiling at Fred Hutch in Seattle. Get in touch directly or apply online:
careers-fhcrc.icims.com/jobs/20178/job…
careers-fhcrc.icims.com/jobs/20179/job…

CMV exposure in SCT donors leaves a lasting immunological impression.

Albert C. Yeh, MD & Hill Lab, Clinical Research Division Fred Hutchinson Cancer Center, find new links between a CMV-specific memory CD4+ T cell subset and poor stem cell transplant outcomes. Read more: fredhutch.org/en/news/spotli…

Now recruiting members of my new lab! Excited to build a team at the Fred Hutch, starting this fall. #microbiome #BMT #immunology social.icims.com/viewjob/pt1625…

Saw this from my apartment tonight in downtown Seattle - feeling inspired by the our collective humanity during this crisis!

I don’t see this discussed much, but this strong correlation makes me ask a lot of question about this pandemic.

This is the correlation between GDP per capita and confirmed COVID cases (per million people).

Confirmed cases, of course, are only a fraction of all cases.

I've been mulling over the MRC Centre for Global Infectious Disease Analysis modeling report on #COVID19 mitigation and suppression strategies since it was posted on March 16. Although mitigation through social distancing may not solve things I believe we can bring this epidemic under control. 1/19

#coronarvirus Initial reporting likely overestimates mortality (2%) as mild cases underreported. 2009 flu pandemic with initial case fatality at 7% (WHO), but ended up being < 0.1%. Still need to take precautions, wash hands, get flu shot, and help curb spread!