Wow.

(It's not clear that the boost to downstream outcomes like flyouts could hold in long-run equilibrium, or that added visibility really is the mechanism driving it. But still, pretty striking, QED!)

Imagine this:
... in vivo gene edit of hematopoiesis for a genetic disease ...
... combined with a second edit (see below) ...
... and then safely removing the unedited cells to heal hematopoiesis!
No need to imagine - it's right here!!
👏Team Cimeio Therapeutics
nature.com/articles/s4158…

Ravi Madduri Tutorials to run SAIGE-GPU: exascale-genomics.github.io/SAIGE-GPU/#/ Docker and singularity containers for deployment on various cloud infrastructures are available.

Excited to share our latest preprint introducing SAIGE-QTL, a powerful tool for single-cell eQTL analysis! Check it out here: medrxiv.org/content/10.110… #eQTL #scRNAseq #genomics (1/9)

An update on our search for the genetic basis of Meerkat Cardiomyopathy from @katherinejwu in The Atlantic today theatlantic.com/science/archiv…

This is a fascinating paper in Nature this week: increasing the weight loss capacity of semaglutide (Ozempic - the GLP-1 receptor agonist)

The idea is to combine GLP-1 with an NMDA receptor antagonist (known to rewire the brain, and previously linked with weight loss) in a

Extraordinary finding from the Global Burden of Disease Study 2021 - The Lancet “Among the specific risk factors analysed for this study, particulate matter air pollution was the leading contributor to the global disease burden in 2021” thelancet.com/journals/lance…

Early career folks: you should submit to the Genomic and Precision Medicine Early Career competition at #AHA24 . Submit your science by June 6, then apply. See bit.ly/3pSegR6 for details

#AHA100years in Chicago, Nov. 16-18

AHA Science
AHA Council on Genomic and Precision Medicine
UCSF Cardiology

🔥 Hiring a funded postdoctoral fellow position in human genetics! Come join us CGM at MGH Broad Institute Harvard Medical School!
🔥 Apply: partners.taleo.net/careersection/…

Overjoyed to congratulate my mentee, James Brogan Vanderbilt Internal Medicine Residency, for being selected by ASH to receive the ASH Hematology Opportunities for the Next Generation of Research Scientists (HONORS) Award! It's a privilege to see you join the ranks of dedicated

Delighted to share our preprint on mapping the genetic association with intra-individual variability of gene expression. We introduced a new statistical framework to identify single-cell variance eQTL and applied it to OneK1K cohort.
biorxiv.org/content/10.110…

Congratulations Yash Pershad & Tara Mack! Vanderbilt MSTP Vanderbilt Genetics Institute Vanderbilt University Medical Center Vanderbilt School of Medicine

Today we announce the submission to #ClinVar of >32,000 variants evaluated for the return of hereditary disease risk in the AllofUsResearch cohort. Its wonderful to return value to those who contribute their data to biomedical research! More details here: allofus.nih.gov/news-events/an…

Thrilled to share that the Vanderbilt-Ingram Cancer Center MDS team, along with our brave patients and their families, came together for the MDS Foundation 5K! Your strength and spirit inspire us every day. Together, we're stepping forward in the fight against MDS. #MDS5K

Great work from Australia from Prof Andrew Mallett group! Finally implementing WGS also in adults to resolve complex diagnoses. More than 80 health systems in North America routinely employ WGS as a diagnostic tool, but they are all pediatric. Let’s bring this to the adult population

We are at the last stretch so please don’t miss out on this wonderful opportunity and APPLY for the Freeman Hrabowski Scholars program🤩🤩🤩HHMI NEWS

Alexander Bick, MD, PhD, a physician-scientist at VUMC, has received a Hevolution/AFAR New Investigator Award in Aging Biology and Geroscience Research from the AFAR and Hevolution Foundation.

Alex Bick Vanderbilt Genetics Institute

spr.ly/6013j3t6V

📢Our latest contribution - People with #HIV and cancer were 𝟰𝘅 more likely to have #CHIP than similar patients without HIV. The negative impact of CH in patients with cancer is exacerbated in people with HIV. More to come... Anna Coghill Gita Suneja MD MS