🚨Paper out, it was great to be a part of this exciting project led by G. Mallucci and co🔬 👇 PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress | Science www-science-org.ezp.lib.cam.ac.uk/doi/10.1126/sc…

Friends and colleagues, ✉️An invitation to join us in March next year to celebrate the 100th anniversary of the founding of The Company of Biologists, bringing together the communities of Development, J Cell Science, Journal of Experimental Biology, DMM Journal and Biology Open 👀 thenode.biologists.com/biologists-100…

Are you a biological/biomedical scientist looking for a new challenge? We're looking for a Perspectives editor to join our editorial team Science Magazine recruiting.ultipro.com/AME1123ASEM/Jo…

PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress. doi.org/10.1126/scienc…

Congratulations Darvis and co on this fantastic story

#MembraneTrafficking seminars are back! Join Fèlix Campelo Francesca Bottanelli and me for an exciting lineup of speakers in our Sep-Dec '24 season. Fascinating science covering protein secretion, lysosome-secretory pathway crosstalk, lipid trafficking...

Astrocytes exert both gain and loss of function pathologies in ALS, providing a dilemma in therapeutics. Prompted by our recent paper in @BrainComms, we revisited our earlier works in Communications Biology + Nature Neuroscience Nature Portfolio Nature Communications at go.nature.com/4fTJvko for AC lovers.

Check this out! A new level of ER stress response revealed: a UPR mechanism for tuning secretion Congratulations Hesso Farhan and co #ER_literature 👇

The big one is out 🎉 So over the moon to see our latest work with Steph Vassilopoulos published in Science Magazine. Check out how we reveal the unique architecture of clathrin-coated pits and endocytosis at the axon initial segment: science.org/doi/10.1126/sc…

Genetically encoded fluorescent sensors for visualizing polyamine levels, uptake, and distribution biorxiv.org/content/10.110…

This week's selection of articles on #proteostasis thanks to Bims: Biomed News -- biomed.news/bims-proteo/20… Highlight: The unfolded protein response regulates ER exit sites via SNRPB-dependent RNA splicing and contributes to bone development embopress.org/doi/full/10.10…

Preprint alert🚨Did you ever experience issues in labeling kinetics and fluorescence brightness, when working with SNAP-tag in live cells? Our newly developed SNAP-tag2 system might be the solution! 🚀Check out our latest preprint on #bioRxiv: 🔗biorxiv.org/content/10.110… (1/4)

Check this out 👇Congratulations neighbours

Now Online Mechanisms of mechanotransduction and physiological roles of PIEZO channels dlvr.it/TD1r8m

Stress response of membrane-based cell organelles in budding yeast biorxiv.org/content/10.110…

Scheiblich et al 2024 Neuron paper reveals that microglia make connections with neurons use tunneling nanotubes (TNTs) to maintain brain health by exchanging cell organelles, synaptic vesicles, and proteins with neurons. In neurodegenerative diseases, TNTs help clear

The UK DRI's William McEwan & Leo James' Lab (MRC Laboratory of Molecular Biology) have developed new therapies that selectively remove aggregated tau proteins - harnessing the unique capabilities of a protein called TRIM21. The treatment improved symptoms of neurodegeneration in mice👉buff.ly/47ogpFG