B-cell depletion therapy drives elevated surface CD27 levels in Th cells, disrupting interactions with CD70-expressing B cells in multiple sclerosis lesions The Becher Lab Cell Reports Medicine cell.com/cell-reports-m…

Excited to share our new paper Science Magazine All credit goes to my (ex)team members Melissa Ng Immanuel Kwok #LeonardTan #Changming. Special thanks to Andrés Hidalgo, @realFlorentGinhoux and Renato Ostuni for their continuing support and friendship

What happens when Treg cells die? Sara and others from the team depleted Tregs and discovered the cytokine networks underpinning the fatal immunopathology. Have a read and let us know what you think. biorxiv.org/cgi/content/sh…

Full of excitement and gratitude to be awarded an #ERCAdG by European Research Council (ERC). This is owed to fantastic work by The Platten Lab DKFZ Neurologie_Mannheim Universitätsmedizin Mannheim Uni Heidelberg. In our project we will study the genetic programs underlying brain tumor-reactive T cells 1/

Twin study dissects CXCR3+ memory B cells as non-heritable feature in multiple sclerosis - read the recent study between Florian Ingelfinger, The Becher Lab & the van Luijn lab in Med by Cell Press #AAI2024 hubs.ly/Q02vSsRM0

Check out our new preprint on tissue-resident macrophages in the pituitary gland! Great work by (twitterless) Henna and Heli Jokela together with our collaborators @realFlorentGinhoux, The Becher Lab, Melanie Greter, and Research group of Professor Marko Salmi! Rantakari Group TurkuBioscience InFLAMES Flagship

Check out ⁦Lugli Lab⁩’s latest great study! 👇NaCl enhances CD8+ T cell effector functions in cancer immunotherapy | Nature Immunology nature.com/articles/s4159…

We think this is a good step in the right direction to use machine-learning to find blasts. Identification of single-cell blasts in pediatric acute myeloid leukemia using an autoencoder life-science-alliance.org/content/7/11/e…

Great fun to explore this with physician/scientists who are true experts in the field (Tobias and Roland). I learned a lot nature.com/articles/s4157… bb