#KRAS alert! Over the past 4 years, a multi-disciplinary team from Johns Hopkins Kimmel Cancer Center Vanderbilt-Ingram Cancer Center Dana-Farber Memorial Sloan Kettering Cancer Center & Amgen 🧪🔬🧬 has been studying the distribution and co-mutations of KRAS, NRAS and HRAS mutant #cancers under the auspices of AACR project #GENIE. Read the 🧵

Congrats to our stellar graduate student Blair Landon for her scholar-in-training award for her #AACR23 abstract on liquid biopsy analyses for patients with #immunotherapy treated esophageal cancer! CMM JHU Molecular OncologyLab Johns Hopkins Thoracic Oncology AACR #proudmentor #WomenInScience

#AACR23, Molecular OncologyLab #1/7: CMM JHU student extraordinaire Blair Landon will present her work on ctDNA analyses in predicting tumor regression with neoadjuvant immuno-chemotherapy for patients with operable esophagogastric cancer. Johns Hopkins Kimmel Cancer Center Johns Hopkins Thoracic Oncology

Cannot think of a better way to celebrate our Nature Medicine #liquidbiopsy study than with the Molecular OncologyLab family (wet lab part pictured 😀)! Fortunate to be surrounded by such talented & driven scientists! Lavanya Sivapalan Maria Fatteh Mimi Najjar, MD Blair Landon + more

So fortunate to celebrate the holiday season with the Molecular OncologyLab! Cannot think of a more dynamic, creative and more importantly good-hearted group of people🙏

Congrats to our super⭐️ Molecular OncologyLab members Blair Landon Lavanya Sivapalan Maria Fatteh for their #AACR24 Scholar-in-Training awards! While the awards are theirs, the pride is contagiously mine 😁😁 AACR Johns Hopkins Kimmel Cancer Center Johns Hopkins Thoracic Oncology Johns Hopkins Molecular Tumor Board CMM JHU Johns Hopkins Postdoctoral Association (JHPDA)

Here's our latest from Johns Hopkins Thoracic Oncology & Molecular OncologyLab, hot-off-the-press in Nature Medicine. What do we learn from neoadjuvant anti-PD1 & anti-LAG3 through the lens of liquid biopsies? Enjoy the read! nature.com/articles/s4159… Vincent Lam Cancer Research Institute Blair Landon

Monitoring DNA shed by tumors into the bloodstream could indicate gastroesophageal cancer response to treatment: study led by Johns Hopkins Kimmel Cancer Center investigators. bit.ly/4aaRtBU

In a phase 1b trial in #GastroesophagealCancer, neoadjuvant nivolumab or nivolumab/relatlimab prior chemoradiotherapy were well tolerated and liquid biopsy analyses show that undetectable ctDNA was associated with longer survival Elsa Anagnostou Vincent Lam nature.com/articles/s4159…

The Molecular OncologyLab is on the way to #AACR24! Hope to see everyone at our presentations & poster sessions covering #liquidbiopsies #cancergenomics, #Immunotherapy #PrecisionOncology! + celebrating 3⃣ scholar-in-training awards! AACR Blair Landon Lavanya Sivapalan Maria Fatteh

At the #AACR24 #LiquidBiopsies session? Check out this phase 1b trial of neoadjuvant #immunotherapy in esophageal/GEJ cancer led by speaker Elsa Anagnostou. Results show that undetectable ctDNA was associated with longer survival Johns Hopkins Kimmel Cancer Center Vincent Lam nature.com/articles/s4159…

Celebrating our trailblazer #womeninscience lab members recognised at the #AACR24 #WICR 25th anniversary session! Akshaya Annapragada Blair Landon Maria Fatteh Lavanya Sivapalan Molecular OncologyLab Johns Hopkins Molecular Tumor Board Johns Hopkins Medicine AACR

Analysis of responders/non-responders to epigenetic priming of metastatic #NSCLC after progression on immunotx -> More antigen presentation & inflammatory response in responders. Use of epigenetic priming to reverse immunotx resistance? Blair Landon Dr. Julie Brahmer #AACR24

Running in between concurrent #AACR24 mini-symposia for our ⭐️ Molecular OncologyLab young investigators' oral presentations! Congrats Lavanya Sivapalan and Blair Landon for stellar presentations and AACR scholar-in-training awards! Johns Hopkins Medicine Johns Hopkins Thoracic Oncology CMM JHU

Last #AACR24 presentation from Molecular OncologyLab happening now in the poster session! Blair Landon our talented CMM JHU grad student seconds her mini-symposium presentation with more evidence of TME reshaping and induction of inflammatory responses with epigenetic tx. AACR

Great to see the wealth and breadth of the Johns Hopkins Kimmel Cancer Center young investigators presenting their work today! Michael Conroy Maria Fatteh Mimi Najjar, MD Blair Landon Lavanya Sivapalan Archana Balan Johns Hopkins Thoracic Oncology Molecular OncologyLab Johns Hopkins Molecular Tumor Board