Share your research w/ organizers Kivanc Birsoy Kivanc Birsoy Rockefeller University, Roberto Zoncu Roberto Zoncu UC Berkeley, Krista Bledsoe Molecular Cell, Allyson Evans セルメタ #CSMetabolites2025 abstract deadline Jan 24 hubs.ly/Q02MVV8z0

In this week’s Editors’ Choice piece, we highlight the work of Zhu and colleagues in Cell Metabolism, showing that the proliferation of somatic clones deficient in PKD1 prevents fatty liver disease without causing tumors. scim.ag/8cI

Register for Cell Symposia #CSMito2024 and join us in Sitges, Spain this October for some inspiring talks, including one from Michal Minczuk Minczuk Lab on the potential of mitochondrial genome engineering hubs.li/Q02Nj91R0

Our editor Mari-Carmen is attending the PARIS MASH Meeting this week. Please make sure to reach out if you´d like to discuss your research with her! Paris MASH Meeting #MASH2024 #MASLD paris-mash.org

Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation dlvr.it/TCmNLM

Nearly 40% of professional and recreational athletes do not consume enough energy to match their energy expenditure. Such chronic energy deficiency compromises metabolic, physiological, reproductive, bone and mental health. Here is a mouse model of this syndrome. Wu Tsai Human Performance Alliance

Biological and genetic determinants of glycolysis: Phosphofructokinase isoforms boost energy status of stored red blood cells and transfusion outcomes dlvr.it/TCmyYw

Great summary of our Cell Metabolism study by Yang Xia's and colleagues - cell.com/cell-metabolis…

Great piece from S. Biffo, Davide Ruggero and TheSantoroLab in Cell Metabolism The crosstalk between metabolism and translation cell.com/cell-metabolis…

TNF compromises intestinal bile-acid tolerance dictating colitis progression and limited infliximab response dlvr.it/TCpYgS

Development of a functional beige fat cell line uncovers independent subclasses of cells expressing UCP1 and the futile creatine cycle dlvr.it/TCq1Fd

#NewIssue Ft cover art by Kehuitang Art Studio. He et al. reveal a protective effect of acetate against metabolic and cognitive impairments caused by sleep disruption. Inspired by Monet’s famous Water Lilies paintings, a “mitochondrion” boat drifts in a lotus pond full of water

Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes dlvr.it/TCqbRj

Professor Satchin Panda and team created a landmark tool for studying relative energy deficiency in sport (REDs), which effects >40% of athletes bone and organ health, sleep, stress, and more 💪💤 Now more effective diagnosis of and treatments for REDs are on the horizon 🏅

Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome dlvr.it/TCs6z8

SLC25A48 controls mitochondrial choline import and metabolism dlvr.it/TCsYV7

Zinc transporter 1 functions in copper uptake and cuproptosis dlvr.it/TCt89B

Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism dlvr.it/TCvcsl

Physical exercise mediates cortical synaptic protein lactylation to improve stress resilience dlvr.it/TCw1tP

Acetate enables metabolic fitness and cognitive performance during sleep disruption dlvr.it/TCwZHB