Editorial from Emanuel Gonçalves & FrezzaLab on how single-cell omics and metabolic models can be used to interpret which mutations are cancer drivers, how clones are selected during tumorigenesis/treatment, and thus suggest novel therapy. genomebiology.biomedcentral.com/articles/10.11…

⚡ Work by Serena Nik-Zainal systematically defined mechs & mutational signatures induced by DNA damage sources Paper Nature Cancer 👇 go.nature.com/3zG5ncq #WorldCancerResearchDay #Sept24th #ResearchWorks #LetsTeamUpForCancerResearch WCRD Cancer at Nature Portfolio Cambridge University

“Is this a prank?” That’s how Abdulrazak Gurnah reacted when he found out that he was the winner of this year’s Nobel prize in Literature. The Tanzanian writer spoke to Jon Snow about his journey. channel4.com/news/abdulraza…

Would be even better if they offered it to all aged 5 years and older ..

How #HybridWorking took hold in science by #KendallPowell Thanks for featuring our team!☺️ T'was a tragic, sudden shut down, lost all our organoids, haven't gone back to old way of working, likely never will. Salute my team💖for embracing the challenge! nature.com/articles/d4158…

Très grand match pour les verts 🇩🇿 et victoire ✌️ pour le Cameroun 🇨🇲 ainsi peut être le football ⚽ !!! Malgré tout 1 2 3 viva l'Algérie. Un grand bravo 👏 pour nos joueurs, respect pour l'entraîneur. Félicitations Cameroun.

Amazing!! 🤩 And also 😱… why does it look like something out of a horror movie..

PAPER OUT!!! 🎉😄💃🏻🕺🏻 Single & double substitution signatures of #100kGenomesProject validated with #ICGC & #Hartwig data🙏 Cannot be achieved without contributions #NHSpatients nationwide🇬🇧🥲#visionary Genomics England Andrea Degasperi tweetorial 2moro! science.org/doi/10.1126/sc…

To coincide with the team's paper release, Signal has been updated to include the more than 50 new mutational signatures across more than 18,000 cancer samples.

• Study hard. • What others think of you is none of your business. • It's OK not to have all the answers. • Experiment, Fail, Learn and Repeat. • Knowledge comes from experience. • Imagination is important. • Do what interests you the most. • Stay curious

PAPER OUT!! 🥳😁 Let me share a #tweetorial about how a nerd moment 🤓when Foad Rouhani & I were PhD students >10yrs ago (!) has (finally) arrived Nature Genetics with implications in using #hiPSCs in clinical studies & research modelling 1/ nature.com/articles/s4158…

A large-scale, whole-genome analysis in Science of over 12,000 cancers reveals previously unreported mutational signatures, including tumor-specific rare signatures. The findings could potentially help enhance personalized cancer treatments and diagnoses. fcld.ly/1cugdml

UK's first #EarlyCancerInstitute is launched in ⁦Cambridge University⁩ 🥳🎉 That’s where we are! Looking forward to the launch today! ⁦Early Cancer Institute, University of Cambridge⁩ bbc.co.uk/news/uk-englan…

Prof Rebecca Fitzgerald outlines her vision for the Early Cancer Institute at the launch of the UK’s first institute dedicated to early cancer research. Cambridge University Early Cancer Institute, University of Cambridge

Cherif BADJA opens the submitted abstracts #BSGM2022 discussing the genetic integrity of #iPSCs Signature analysis suggests UV ☀️ / oxidative damage BCOR driver mutations seen (not UV), affect differentiation Published in Nature Genetics nature.com/articles/s4158… Serena Nik-Zainal

Serena Nik-Zainal (University of Cambridge) speaking on- Utilising the full potential of cancer whole genome sequencing: advances and challenges in the NHS #BSGM2022 UK Cancer Genetics Group BSGM ACGS AGNC Cambridge University

A rare genetic disorder provides insights into mechanisms of early-onset neurodegeneration medrxiv.org/cgi/content/sh… #medRxiv

x.com/megatron_ron/s…

Megatron Israel claimed 1,500+ Israelis were killed by Hamas on Oct 7. 40 babies were beheaded. Israel has since dialed the number back to 1,400, then 1,200, but they have only 1,085 names, 350 of whom were military. There was only 1 baby. Many killed by IDF "friendly fire," not Hamas.

PAPER OUT!!🥳 It's on kids with #XP A DNA repair defective syndrome where patients are unable to fix UV damage in skin. Used 2 die as kids from Skin Cancer. No longer, thx 2 surveillance! But now some live 2 adulthood & develop early-onset dementia.. 1/n cell.com/cell-reports/f…