DORTMUND! ⬅️😍➡️ #NothingLikeOranje #NEDENG

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Postdoc in Medicinal Chemistry & Molecular Glue discovery wanted! Combine advanced organic chemistry & cutting edge drug discovery in a vibrant, international team? Further infos: chemie.tu-darmstadt.de/hausch/group_m…

Ever wondered how (often) inhibitors degrade their targets? Then you should check out our latest preprint : “Inhibitor-induced supercharging of kinase turnover via endogenous proteolytic circuits”, led by the fantastic natalie_scholes biorxiv.org/content/10.110… explanation 🧵👇

Excited to share our latest preprint on developing the first selective class IIb HDAC #degraders! Thrilled to see the #TPD community growing in Bonn Radek Nowak Christian Steinebach ! Huge congrats to first author Shiyang Shiyang Zhai and the entire team! - go.shr.lc/3LqRQhm

Very happy that my co-workers Linda and Felix could contribute #HDAC inhibition and viability assay data to this exciting project led by the Mahboobi lab! sciencedirect.com/science/articl…

We thank the reviewers for their helpful suggestion

Development of a NanoBRET Assay Platform to Detect Intracellular Ligands for the Chemokine Receptors CCR6 and CXCR1 (F. K. Hansen, M. Schiedel et al.) Finn K. Hansen, Matthias Schiedel #openaccess onlinelibrary.wiley.com/doi/10.1002/cm…

The University of Bonn offers two PhD scholarship financed by the DAAD within the DAAD-GSSP Programme. The PhD students will be associated to the Research Training Group RTG/GRK 2873 GRK2873. Apply now! Please RT. grk2873.uni-bonn.de/en/training-pr…

We are looking for a Scientist to join us in the Fischer lab to work on proteomics-based projects. If you are interested in big data problems and using proteomics as a research tool take a look at the job description and apply now! careers.dana-farber.org/job/8602/scien…

Do you want to target Methyl-Transferase-Like proteins ? Keep calm and... count to 16!!! #SPOTSLab Department of Pharmacy Unina pubs.acs.org/doi/10.1021/ac…

Check out our PoC study on a trivalent degrader that leverages dual ligase recruitment to enhance target degradation. Led Adam B. in Alessio Ciulli 's lab, Miquel M. and Cecilia B (Promega). Many future implications, also regarding resistance acquisition. tinyurl.com/2mz4btvz

Happy to share the latest tricks of the CalpL protease, which turns out to be a ring nuclease, too. A great team effort by Sophie Binder, Niels Schneberger, Maximilian Schmitz, Christophe. Rouillon and Marianne Engeser. academic.oup.com/nar/article/do…

Happy that my postdoc Linda could contribute the HDAC inhibition data to this nice work from the Kalinina lab Universität Münster. Congrats to everybody involved! link.springer.com/article/10.100…

Excited to share our preprint on developing a fluorescent probe that led to the discovery of enhanced antagonists for the IABS of CCR7! A huge thank you to all collaborators for the incredible teamwork! Philipps-Universität Rheinische Friedrich-Wilhelms-Universität Bonn Baumjohann Lab Matthias Schiedel biorxiv.org/content/10.110…

Excited to share our latest paper on heteroaryl-decorated HDAC inhibitors with dual-stage antiplasmodial activity, now published in Eur. J. Med. Chem.! Huge congrats to first author Daniel Daniel Stopper and the entire team! sciencedirect.com/science/articl…

If you're at #EFMCISMC24, visit the Chemistry Europe table at EFMC Booth #59. Get some Wiley Chemistry book discounts, writing guides & freebies and meet our EiC! Then visit the EFMC Young Scientists Network Photo Booth to our left & chat with some YSN volunteers! EFMC #medchem #chembio

Great lab, Great PI! Apply!

I am excited to announce I am a recipient of the Joanna Fowler award from Brookhaven Women in Science (BWIS) . Thank you to ChristiansonLaboratory for his support during my Ph.D. And to all the macromolecular beamline scientists at Brookhaven Lab who made my research possible! bnl.gov/newsroom/news.…

Congrats to postdoc Juana Goulart Stollmaier Juana G. Stollmaier and group alum Dr Paris Watson for this fantastic work, just published in ACS Med Chem Lett ACS Publications Bio & Med Chem Content! HDAC10 catalyzes thioester hydrolysis to activate thiol-containing pharmacophores. pubs.acs.org/doi/10.1021/ac…