we're recruiting for a postdoctoral fellow to work on machine learning approaches to identify therapeutic targets (synthetic lethality) using networks in cancer. please RT. #postdocjobs #sciencejobs cancerdata.ucd.ie/vacancies/

Last chance to apply for this PhD opportunity in our lab - deadline on Friday! tinyurl.com/58krm45b A combination of bioinformatics and in vitro modelling of human development to explore how genetic variation drives craniofacial diversity and disease.

We're hiring! The College of Medicine & Vet Medicine is looking for three Research Data Managers. One post holder will be attached to the Institute of Genetics and Cancer and work closely with me and my team in the Bioinformatics Analysis Core. elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…

We're recruiting a post-doc for a project that will use single-cell genomics approaches to discover mechanisms of oncogenic chromatin regulation in childhood cancers. Apply here: elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…

Excited to share that our paper is out NatureStructMolBiol. Spearheaded by the amazing Nezha Benabdallah who is starting her own lab next year 🤩. We show that the SSX C tail of SSX oncofusions provides specificity to H2AK119ub1-rich regions and further promotes PRC1.1 complex stability.

Aberrant gene expression in cancer is often complex. Here, we show how a single fusion protein, involving SSX, anchors activators to polycomb targets, leading to synovial sarcoma. Take a look! nature.com/articles/s4159…

New paper from my group, in which we use the combined power of AlphaFold and biochemical reconstitution to determine how the Rrm3 helicase is targetted to the eukaryotic replisome embopress.org/doi/epdf/10.10…

Our latest manuscript on a new cell cycle dependent control of dna repair. Started from a high resolution crispr screen of #ubiquitin system after IR: check table S2! Also substrates of cyclin f through motif search! science.org/doi/10.1126/sc…

For #ChildhoodCancerAwarenessMonth we spoke to Gerard Brien about his work @edincrc to make discoveries that will have a tangible impact for patients and their families: bit.ly/4dNAKGQ

We are looking for an enthusiastic Wellcome-funded Lab Manager and Research Associate to help run our lab and facilitate discoveries on centromere formation. Join us at Department of Biochemistry at Oxford University! sites.google.com/view/jansenlab…

Exploring DNA repair pathways 🧬 Join the keynote lecture chaired by Charlie Gourley for insights into the journey of discovery & perseverance in cancer research. The University of Edinburgh | #ESMO2024 | #CRUKFunded