The 2021 European consensus statement on the diagnosis and management of #migraine is closing in on 100,000 reads 🌟🧠 The consensus statement is freely available on: nature.com/articles/s4158… Nat Rev Neurology European Academy of Neurology European Headache Federation International Headache Society EMHA- European Migraine and Headache Alliance

Congrats to Hakan Ashina for receiving the LF Early-Career Clinician Scientist Grant worth USD 250,000 from Lundbeckfonden 🌟 We are excited to see your innovative research on mapping signaling mechanisms in post-traumatic headache 🧠 lundbeckfonden.com/mapping-signal…

Exploring the relationship of neck pain with #migraine and tension-type #headache. This review by Haidar Al-Khazali & colleagues delves into the prevalence, pathophysiology, and management strategies 🧐🧠 👉 sciencedirect.com/science/articl…

Just in! 📢 New study in J Headache Pain revealing that #CGRP appears to play an important role in #migraine aura! 🧐 This indicates that CGRP can trigger cortical spreading depolarization (CSD)! 🌟🗞️ Read more: …alofheadacheandpain.biomedcentral.com/articles/10.11… European Headache Federation Messoud Ashina

Lovely networking after 9 hours of discussing headache at the #iHead2023 #ihc2023 International Headache Society

Just in! New study in Cephalalgia shows that cutaneous #allodynia might increase odds of CGRP-induced #migraine attacks, while migraine with #aura reduces them 🔍 However, both factors lost significance after Bonferroni correction 🧐 Read more: journals.sagepub.com/doi/10.1177/03…

Exciting breakthrough 👉PACAP-38 identified as a possible pathogenic driver in post-traumatic headache 🧐 Targeting PACAP signaling might be a promising approach to treat post-traumatic headache 🔍 Read the paper in Brain here: academic.oup.com/brain/advance-…

Al-Khazali et al. show in a randomized placebo-controlled trial that intravenous infusion of PACAP-38 is a potent inducer of migraine-like headache in people with persistent post-traumatic headache resulting from mild TBI. tinyurl.com/449awssb

Friday news 🗞️ Novel findings reveal that KATP channel opening can induce migraine-like headache in people with post-traumatic headache 🔍 This could pave the way for new treatments targeting KATP channels 🌟 Read more: journals.sagepub.com/doi/10.1177/03… Hakan Ashina Haidar Al-Khazali

Just in 📢 New research paper in PAIN Journal finds that KATP channel opening triggers cluster #headache attacks, but not during remission periods 🧠💡 Could selective KATP channel blockers be a new treatment path? 🧐 Read more: journals.lww.com/pain/abstract/…

Al-Khazali et al. found levcromakalim (KATP channel opener) triggered migraine-like headache in people with persistent post-traumatic headache (PTH). KATP channel blockers might represent a promising treatment option in PTH. Haidar Al-Khazali #headache doi.pulse.ly/l3owiexnht

🗞️ New international guidelines for clinical trials on post-traumatic headache by Hakan Ashina & International Headache Society 🧠🌟 👉 Read more here: journals.sagepub.com/doi/10.1177/03… #headache #clinicaltrials #concussion #TBI

Hot off the press 🗞️ Upregulation of intracellular cAMP triggers migraine-like headache in people with post-traumatic headache 🧠 Could targeting cAMP-dependent signaling be the key to pain relief? 🧐🧠 Read more here: …alofheadacheandpain.biomedcentral.com/articles/10.11… Hakan Ashina Haidar Al-Khazali

Now in #PAIN: “Induction of cluster headache after opening of adenosine triphosphate-sensitive potassium channels: a randomized clinical trial” by Haidar Al-Khazali et al. bit.ly/3K0UtWd

🔬 New research paper finds hypersensitivity to BKCa channel opening in people with post-traumatic headache🧠 Targeting BKCa channels might open new avenues for drug discovery 💊Hakan Ashina Haidar Al-Khazali Basit Ali Chaudhry Read more here: …alofheadacheandpain.biomedcentral.com/articles/10.11…

Our recent study shows #migraine patients face more significant neck pain-related disability compared to those with tension-type headache. There is a need for better targeted pain management strategies #headache 👇rb.gy/ycl6n5

🚨 New hope for people with migraine! A Phase 2 study shows that a monoclonal antibody against PACAP reduces migraine days. 🌟⁦⁦Rigshospitalet⁩ ⁦⁦⁦International Headache Society⁩ ⁦Lundbeckfonden⁩ ⁦Human Migraine Research Unit⁩ ⁦European Headache Federation⁩ nejm.org/doi/full/10.10…

Al-Khazali et al. show that individuals with migraine experience more problems related to neck pain compared to those with tension-type headache and healthy individuals without headache. journals.sagepub.com/doi/10.1177/03… #headache #migraine Haidar Al-Khazali Sait Ashina HenrikSchytz

Some triptans are a more effective treatment for acute migraines than newer, more expensive drugs, finds an analysis of the latest evidence Andrea Cipriani Includes a visual abstract #BMJInfographic bmj.com/content/386/bm…

Thursday News 🗞️ Excited to announce our latest paper in The BMJ: a network meta-analysis comparing 17 acute #migraine meds 💊. Eletriptan, Rizatriptan, Sumatriptan, & Zolmitriptan outshine newer #CGRP-targeted treatments 🧠bmj.com/content/386/bm… bmj.com/content/386/bm…