What are adequate levels for risankizumab? Trial data wasn't as convincing. Any recommendations on what we should aim for? Do we need to aim higher for fistulizing/ penetrating disease? #TDM #IBD #monitoring

PIANO Digestive Disease Week !
✅Pregnancy IBD: Preliminary Results from Helmsley Global Consensus Conference: May 19 10-11:30
✅WOUND HEALING AFTER EPISIOTOMY AND CESAREAN SECTION AMONG WOMEN WITH IBD
May 20 800-815
✅USE OF BIOSIMILARS TO IFX DURING PREGNANCY IN WOMEN IBD May 20:1230-130

Excited to hear from Robert Harrington on The Future of Clinical Trials at our Houston Methodist MD Dept of Medicine Annual Celebration. #research Houston Methodist Residency & Fellowship Programs Weill Cornell Medicine #medtwitter #meded

Introducing the African IBD Research Endeavour (AIRE) - privilege to be at the inaugural meeting of this group. Our aim is to fill the gaping gap in research & understanding of causes of rising incidence of IBD in Sub-Saharan Africa. 🇳🇬🇸🇱🇰🇪🇿🇦🇬🇭🇿🇲🇿🇼 🧬 🦠 🚬 🍔 🏭

Any well done study involving diet in IBD can benefit our patients and add to our evidence base. #IBD #diet

That’s a Wrap for the EBMed Great GI Debates 2024!

Recap of an amazing weekend ☀️

Glad I got to meet such an amazing group of talented people.

Thank you #EBMed for this amazing opportunity as a trainee travel scholarship awardee.

Treatment Algorithm for Managing C. difficile infection in 2024

1️⃣ 1st Episode
2️⃣ 2nd Episode
3️⃣ 3rd Episode

▪️Fidaxomicin > vancomycin
▪️Look for risk factor - use BEZ
▪️Use Microbiota replacement therapy (MRT)

🙏Dr. Paul Feuerstadt

#EBMed

Diagnosis of C. difficile infection

▪️Understand what you are ordering
▪️2 assays are better than 1
▪️At least 1 should include the ElA
▪️The other can be GDH or PCR
▪️If the GDH used & results are discordant, then reflex to PCR to confirm the diagnosis!

#EBMed

Prior studies have cited gut dysbiosis as a catalyst for inflammatory skin conditions, but this interesting new study suggests that damage to the skin may actually alter the gut microbiome.

nature.com/articles/s4146…

#crohns #crohns disease #IBD

Short Bowel Syndrome Mgmt is complex! Dr Novak Mount Sinai IBD Center expertly guides us

✂️Read op note
3️⃣Types of intestinal failure

Rx
💦 intake & iso-osmol
🍟⬆️SCFA,⬆️protein,⬇️simple CHO
💊<100cm ileal ✂️ bile acid binder
🔥PPI+anti💩
💉TPN+vitamins
💊Teduglutide (GLP-2) helps QoL

Dr Paul Feuerstadt discusses lapses in implementing the evidence for C diff management.

🤔When will fidoxamicin (1st line) be more affordable? 2025.
💩we are missing out on bezlotoxumab opportunities?
🥲 mistakes in handling restorative microbiota therapy

Recording on…

#EBMed (Golden) Cocktail Hour
#FabulousFaculty 📸📸

The Sami(ee)r Sandwich gets bigger and bigger!!

Sometimes I get asked about stem-cell transplantation (SCT) for IBD

☑️The Lancet Gastroenterology & Hepatology 👇🏾

🟢bold idea + brave pts + investigators.

🔴 risk of SCT >>>> risk of IBD
🔴SCT not better than standard tx

🔴don’t trade morbidity for mortality?

thelancet.com/journals/langa…

How to do we become a good patient advocate?

Aline Charabaty, MD, FACG, AGAF & Amber Tresca breaks it down @ #EBMed

📍🗣️ to patients
🤝 Shared decision making w/ pts
✅ solutions to systemic barriers
✅ Communication establishes trust 💯

#GITwitter

Nice to be labelled royalty in the #IBD world and an honor to join the panel with Dr Marla Dubinsky in discussing our clinical interpretation of research. #GI

Truly and tremendously enjoyed today, grateful for the small group! So many direct opportunities to learn from the giants outside of my institution. Feeling pumped 💪and inspired.
Rukaiya Bashir Hamidu, MD || Rukkss!! Joseph Sleiman, MD Bincy Abraham, MD, MS Katie Dunleavy
#EBMed

How do these #IBD experts (Dr Dubinsky & Bincy Abraham, MD, MS & Evidence-Based GI Doc) critically evaluate clinical trials? #EBMed

👭Know pt population (🗓️ 🔦 😫🔥)
👠Understand study design
💉Induction dosing
🪞EIMS?
🍑Perianal disease?
🦠Diff MOA of biologics for combo 👑
🔦Strict Endo endpoints

Interesting MA of RCTs of DCE v HD-WL for dysplasia in IBD @Dr. Samir A Shah AJG - The American Journal of Gastroenterology

☑️DCE > HDWL for fraction of pts with at least one dysplasia (19% v 9%)

⏺️low heterogeneity.

⏺️ implies targeted (DCE) > Rand. bx?

✅ I use NBI - what do you use?

journals.lww.com/ajg/abstract/2…

Is it possible to have this much fun at a medical conference while networking and learning about each other?! Should be the norm!