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Meta-analysis found retrospective measures of childhood maltreatment link more strongly with psychopathology than prospective measures, suggesting that subjective interpretation is a key target for intervention. ja.ma/3ArZyFz Dr Jessie Baldwin Andrea Danese

Having persistently raised levels of inflammation as measured by CRP throughout childhood and adolescence, peaking at age 9, was associated with increased risk of developing psychosis disorder, severe depression, and higher levels of insulin resistance. ja.ma/3Xd5NpW

Controlling for genetic and environmental confounding, study revealed 21-41% of mental health conditions in Australia are attributable to child maltreatment. Over 1.8 million cases & 184,000 DALYs could be prevented if child maltreatment was eliminated. ja.ma/4cyHAij

Incidence of mental illnesses was elevated for up to a year following severe COVID-19 in unvaccinated people. These findings suggest that vaccination may mitigate the adverse effects of COVID-19 on mental health. ja.ma/4dRTrZw

Incidence of mental illnesses was elevated for up to a year following severe COVID-19 in unvaccinated people. These findings suggest that vaccination may mitigate the adverse effects of COVID-19 on mental health. ja.ma/4duftBT

Most viewed in the last 7 days from JAMA Psychiatry: What are the associations between mental illnesses and diagnosed COVID-19 by vaccination status in patients hospitalized for COVID-19 and the general population? ja.ma/3T0MaPm

Viewpoint discusses clinical trial results of GLP-1 receptor agonists for treating the weight gain and cardiovascular disease risk of psychiatric medications. ja.ma/4duftSp

Parent-offspring transmission of adverse stress responses or PTSD was correlated with both rearing and genes. ja.ma/3YAiDzF

Results of this study suggest that persistent shorter sleep duration across childhood was associated w/ higher risk of developing psychosis in young adulthood. Inflammation as measured by IL-6 level could be one of the potential mechanistic pathways. ja.ma/3SFUJPl

Plasma levels of p-tau181 and NfL may be used as a biomarker for psychosis in mild cognitive impairment and Alzheimer disease, with potential implications for disease monitoring and treatment strategies. ja.ma/46A3Oz1

Polygenic risk scores predict psychosis concordance in twin study, highlighting genetic liability in schizophrenia and bipolar disorder even in small samples. ja.ma/3X7xYFk

Accounting for prominent nonlinearities in the association between cognition and psychiatric symptoms may be able to better capture between-child heterogeneity and resolve ostensibly conflicting results in studies assaying dissimilar symptom severities. ja.ma/3X7B3W3

In this repeated cross-sectional study, there was no evidence that state-level recreational marijuana laws were associated with encouraging youth marijuana use, based on both the logistic regression and interaction-weighted models. ja.ma/3YYePbp

Most viewed in the last 7 days from JAMA Psychiatry: What are the associations between mental illnesses and diagnosed COVID-19 by vaccination status in patients hospitalized for COVID-19 and the general population? ja.ma/3MhGpsF

Most viewed in the last 7 days from JAMA Psychiatry: Are inflammatory biomarkers associated with subsequent risk of psychiatric disorders? ja.ma/4dInjIf

This article describes the process used to develop clinical practice guidelines for the Department of Veterans Affairs (VA) and Department of Defense (DoD) and comments on the 2023 VA/DoD guideline for posttraumatic stress disorder. ja.ma/4e34b7w

Inflammatory biomarkers including leukocytes, haptoglobin, CRP, and IgG were associated with a subsequent risk of psychiatric disorders, and thus might be used for high-risk population identification. ja.ma/3MnBaYs

This cohort study examines rural and urban trends in 30-day all-cause and same-cause mental health readmissions in the US. ja.ma/3XnBP2D

In this systematic review and meta-analysis, classic psychedelics were generally well tolerated in clinical or research settings according to the existing literature, although SAEs did occur. ja.ma/4e89vGJ

The risk of suicide is elevated among individuals diagnosed with medical conditions; those with mental disorder appear to be at such elevated risk of suicide that additional disability associated with medical conditions has little impact in this regard. ja.ma/4cPmXyt