Should I delay levodopa to prevent long term adverse events? Jill Ostrem says NO. She says look at the data from Italy and from Ghana and you will see that the evidence does not support delaying levodopa. Levodopa phobia is a real phenomenon and the data should be used in

Next up at #WCN2023 is Jon Stoessl of Djavad Mowafaghian Centre for Brain Health discussing the utility of #neuroimaging in the differential diagnosis of #Parkinsonian disorders.

Jill Ostrem on the advancing edge of DBS for Parkinson's disease at #WCN2023 Adaptive stimulation, beta oscillations, local field potentials, directional sensing, remote tracking

Intrigued to discover more about how DBS reveals & therapeutically impacts on the dysfunctional circuits behind different brain disorders, from OCD to dystonia? 🪄🧠 So were we! Join us on this deep dive from core to cortex – now out Nature Neuroscience: nature.com/articles/s4159… A 🧵

Congratulations to Ann H. Tilton, MD, FAAN, for receiving the 2024 AAN President’s Award! Read more about Dr. Tilton and her amazing accomplishments. bit.ly/3udDGLq #AANAM #NeurologyProud

What a great honor and fun to welcome Dr. Sanjay Gupta to the largest meeting of neurologists in the world American Academy of Neurology 🧠 #AANAM Thanks Dr. Gupta for your work on educating the public on #BrainHealth & #PreventiveNeurology Let’s work together on “what’s possible” for the brain 🙌

STN vs GPi DBS how does an expert choose? ⁦Jill Ostrem⁩ summarizes it nicely in this chart she shared at AAN DBS course. ⁦American Academy of Neurology⁩ ⁦DBS Think Tank⁩ ⁦Lead-DBS⁩

ADAPT DBS closed loop Parkinson trial results announced today by presentation ⁦American Academy of Neurology⁩ by Helen Brontë-Stewart. It was a positive trial and met pre-specified FDA outcomes. Will it be heading to the clinic soon. Next steps will be a full publication and submission to FDA

What is a huge practical challenge for DBS? Multiple systems, multiple platforms and overwhelming for widespread global adoption. Clinicians are frequently befuddled. Mike Pourfar shares his strategy. Will this be AI in future? ⁦American Academy of Neurology⁩ ⁦DBS Think Tank⁩ ⁦

There's never been a disease-modifying drug for Parkinson's disease to slow its progression. Now there may be two emerging. —GLP-1 nejm.org/doi/abs/10.105… NEJM —anti-synuclein antibody nature.com/articles/s4159… NATURE.med

‘The most sacred duty of any leader is to take care of their subordinates.’ We let our Marines down. Caroline Tanner @ucsf with BrianGrantFoundation, Amy Westervelt, Mike Partain and Jerry Ensminger are the heroes leading change and justice for Camp LeJeune victims and also embracing

🚨#preprint alert 🚨 Center For Brain Circuit Therapeutics GPi DBS for dystonia is effective. More recently, STN DBS has been investigated, as an alternative. In what enfolded like a stunning thriller to me, Konstantin Butenko tells a tale of two networks… medrxiv.org/content/10.110… 🧵

Taylor Swift made her debut at her first national neurosurgery meeting in Nashville TN today. Well, these guys wrote this song with her when she was 14. The Warren Brothers and Lee Thomas Miller knocking it out of the park, or should I say hotel ballroom. Taylor Swift

Video-based machine learning can help clinicians predict motor impairment severity for patients w/ #ParkinsonsDisease, a study finds. The system "could support faster & better diagnostics & treatment in the future.” UCSF’s Dr. Simon Little says. ucsfh.org/45ZEoKO

New review paper just out today NEJM on Parkinson's disease by Professors Jill Ostrem and Carlie Tanner UCSF Health. Check out the gems they include like this chart of all the current medication options. I added the 'hot' new article sign as we presented in Aspen

Can you name primary, secondary and tertiatry prevention strategies for Parkinson's disease? Caitlin Agarwal in NEJM was the artist for this supplementary figure which is a gem and you should not miss reading and digesting it, as it is hidden in the supplementary information.

Meet Shawn, a former pro skateboarder diagnosed with Parkinson's nine years ago. With adaptive deep brain stimulation, a personalized algorithm adjusts his treatment as symptoms change. tiny.ucsf.edu/DkD8IY Simon Little UCSF Neurosurgery

The most creative, intense, and rewarding project I’ve ever worked on! Now out Nature Medicine. Real-world blinded adaptive DBS halves time with motor symptoms and improves quality of life in Parkinson’s disease. With the amazing Stephanie Cernera Lauren H Hammer Simon Little Philip

When they go low (beta) we go high (gamma) for adaptive DBS for Parkinson's. Simon Little showing this new Nature Medicine paper w/ three woman first authors which he is very proud of as three rising stars in the field. DBS Think Tank first speaker today showing a paper literally

Congratulations to the winners, very well deserved!!