How do different routes of #mRNA vaccination (made by Tiba Biotech LLC) impact the differentiation and distribution of #vaccine elicited CD8 and CD4 T cell memory responses in mice? Buck O'Flanagan Masopust Vezys Lab NIAID CIVICs 👇🏼 biorxiv.org/content/10.110…

It's out! Very excited to share the Marco Kuenzli and Buck O'Flanagan et al publication on the effects of route on CD8 resident #Tcells. Importantly, intranasal boost after intra-muscular immunization of a self amplifying #mRNAvaccine increased circulating AND resident #Tcells

Former and current lab members Pam Rosato Dr. Sahar Lotfi-Emran, MD, PhD Vineet Sathi Wijeyesinghe Clare Quarnstrom Jason M Schenkel lalit beura and collaborators (Dennis Burton) show CD8+ #TRM + reactivation = ↑ vascular permeability, ↑ neutralizing and #HIV antibody and synergistic mucosal immunity

U of M researchers were able to keep mouse immune cells alive & active for 10 years, longer than 4 mouse lifespans—with huge implications for cancer, vaccination, and aging research! Read more ➡️: bit.ly/3wD3Zby Masopust Vezys Lab | #UMN | #Aging | #Cancer | #Vaccination

Long live #Tcells! Dr. Andrew Soerens and a team in the Masopust Vezys Lab lab at UMN Medical School repeatedly immunized generations of mice, and showed that T cells can proliferate for over 10 years! 🎧 bit.ly/3WX1Ty3 🧵 x.com/masopust_vezys…

Very excited this seminal work by J. Michael Stolley and colleagues on #oral #TRM is published by JExpMed! Be sure to check out the video summary also linked below.

Want to learn more about #CD4 #Tcells? Read our open access recent review by lead author Marco Kuenzli! nature.com/articles/s4159…

Interested in #Tcells in #tumors? Exciting new publication in Science Immunology from our lab with first author Noah Veis Gavil shows that #Trm in tumors have a residence phenotype distinct from healthy tissue #Trm science.org/doi/10.1126/sc…

Very proud of Dr. Noah Gavil on his thesis defense! Happy Cake and Champagne!

Check it out if you want to postdoc with a great lab lalit beura Beura_lab@Brown !

Congrats Dr. Scott! You are a talented and hard working scientist who will do great research in your next adventure.

See our recent review (Katarina Cheng and Noah Veis Gavil ) in Immunity on #Trm like cell (migration is often not assessed) heterogeneity, correlation with favorable prognosis and future areas of study! cell.com/immunity/fullt…