So excited to share the first work from our lab. Led by Steven Pilley with help from lots of amazing collaborators. A special shout out to Lyssiotis Lab and Brian Kennedy and their labs!

After 3 years of planning and fundraising, my Rapamycin & Exercise human trial is ready to start patient recruitment! The study enrolment link is in the pinned comment Thank you all for being so supportive, particularly: - Matt Kaeberlein Matt Kaeberlein for help with the study

We’ve achieved 30% of our funding goal for the groundbreaking mTOR inhibitor screening project! The purpose with this project is to uncover even more potent mTOR inhibitors than Rapamycin when it comes to extending lifespan. If you’re enthusiastic about longevity or want to make

Adress your experience and how this fits into the lab and to the particular project. The application deadline gives you the time to do exactly this homework. All applications within that time will be considered. It doesn't matter if you're first or last sending the application.

New paper from the lab! ALS-FUS mutations cause abnormal PARylation and histone H1.2 interaction, leading to pathological changes: cell.com/cell-reports/f… #ALS

Few days left to apply for PhD or Postdoc positions on comparative genomics to understand long healthspan and disease resistance in bats, as part of our ERC synergy #BATPROTECT.

We are looking for a #physiologist to study how the age-related decline of organ homeostasis, and associated changes in #metabolism and #endocrine systems cross-talk contribute to #diseases of aging across the core therapeutic areas of Novartis. Desirable #ECM #aging knowledge.

Day 3 of the fantastic #ARDD2024 conference. Come see me at my poster #91 if you are interested in transcriptomic aging clocks, stochasticity, and in silico drug screens to prevent neurodegeneration. The preprint 👇 researchsquare.com/article/rs-436…

Our paper is out! Congrats to Saori Takahashi, Hiro Kyogoku, Tomo Kitajima, and everyone involved! We discovered a 2-step transition in DNA replication regulation accompanied by transient genome instability in early mouse embryos. nature.com/articles/s4158…

ARDD 2024: from Big Pharma to big proposals. Aging #drugdiscovery meeting demonstrates longevity is attracting the attention of those outside the geroscience field. @ardd_meeting David Sinclair @andreabmaier Andrew Steele Alex Zhavoronkov, PhD (aka Aleksandrs Zavoronkovs) #longevity #aging bit.ly/4g3pk3n

🚨Faculty Job Alert! 🚨We are excited to announce a new tenure-track faculty search at the Neuroscience Institute for a #theoretical and/or #computational neuroscientist. Apply by 11/15 to join our community! apply.interfolio.com/153167 #neuroscience #academicjobs

Thank you Alex Zhavoronkov, PhD (aka Aleksandrs Zavoronkovs), The Scheibye-Knudsen Lab, and Daniela Bakula for this fantastic conference. Every year it is really one of the most inspiring places to be! Looking forward to #ARDD2025 !

Impressions from #ARDD2024, what we learned and how we can make it even better. geroscience.substack.com/p/impressions-… It was a great ARDD Meeting with Max Unfried Brian Kennedy and VitaDAO 💛

RESULTS: Congratulations to David Meyer, Lu Dong, and Aysevil Pektaş on winning the poster awards 2024!

Aging does not generally compromise gene expression control. Read our paper in Nature Aging on regulatory changes of gene expression control: rdcu.be/dSORY This is fantastic work of Ana Carolina Leote and Francisco Lopes 🎊🥂🎉 #aging #ageing

Preprint on "BWT construction and search at the terabase scale". We can compress 100 human genomes to 11GB in 21 hours, find SMEMs with it, do affine-gap alignment and retrieve similar local haplotypes. 7.3Tb commonly sequenced bacterial genomes ⇒ 30GB arxiv.org/abs/2409.00613

Excited to see my PhD work with Andreas Beyer and Francisco Lopes now online! 🥳🪩 Huge thanks to Andreas and former lab mates for all the support ❤️ We looked at how gene-gene coordination changes with age in 8 human tissues (see🧵👇): nature.com/articles/s4358…

ARDD was so much fun - from enabling speakers to speaking myself. Preprint of the human Lipid Aging Clock presentation out now: medrxiv.org/content/10.110…