Read the latest Curbside Consult article “How Do I Manage Acute Pain for Patients Prescribed Buprenorphine for Opioid Use Disorder?” by Drs. Sukhmeet Sandhu and susan calcaterra: eviden.cc/3UtSwqv

A 73-year-old man presented for evaluation of shortness of breath, weight gain, and leg swelling. A team from West Virginia University’s Camden Clark Medical Center reviews their approach to evaluating this patient in the latest Morning Report. eviden.cc/4b2w0vk

Winnie Roy

This review introduces 5 principles for implementing diagnostics in public health and applies them in two important use cases: the COVID-19 pandemic and antimicrobial resistance. Read the full review: eviden.cc/4djcexI

“Understanding the changing mutational landscape in each tumor over time may provide a ‘signature’ of molecular alterations that would offer insights into the best therapeutic option or one to avoid.” Full editorial: eviden.cc/4daFiak

Maxwell Lloyd #Oncology

“Disparities in the utilization of CAR-T therapy for [large B-cell lymphoma] treatment among minority patients represent a significant challenge in contemporary oncology care.” Read the full editorial by Drs. LaQuisa Hill and Melody Smith: eviden.cc/3x2z1Nv

In the first episode of a four-part Double Take video miniseries, Dr. Shannon Scott-Vernaglia, MD recounts her personal experiences with depression. Watch now: nej.md/4aVmYka

Editorial: “Reflecting the Real World of Cancer Care — The Impact of Broadening Trial Eligibility” by Ramya Ramaswami, MBBS, MPH, and Thomas S. Uldrick, MD, MS eviden.cc/3x0oYIG

“A potential explanation for differential access to CART19 among minoritized racial groups, particularly in highly resourced academic centers, is racial disparity in treatment recommendations.” Read the full editorial: eviden.cc/3TvT2n6

While discussing the results of the MANDALA trial, the hosts of Beyond Journal Club, a podcast by CORE IM in collaboration with NEJM Group, address why albuterol alone is no longer the recommended first-line rescue medication for adult patients with asthma. 1/3

Drs. Christopher J. Yarnell & Michael Fralick review the article by Desai et al. describing methods for individualized treatment effect prediction models using TOPCAT data, calling it an informative example of exploring heterogeneity of treatment effects. eviden.cc/3TuT2DP

“In a randomized, placebo-controlled trial in adults with obesity, intranasal oxytocin administered four times daily for 8 weeks did not reduce body weight.” Read the full trial results: eviden.cc/3UvTFz2

#Endocrinology

Much of what we learned in school about how we taste is wrong. Progress in understanding how taste works is providing insights that may help in the management of obesity, diabetes, and other illnesses. Read the full review: nej.md/4brYn6f

Editorial: “An Assessment of CAR-T Cell Therapy Utilization among Racial and Ethnic Minority Patients” by LaQuisa C. Hill, MD, and Melody Smith, MD, MS eviden.cc/3x2z1Nv