Love my cats- but they’re plant hunting demon spawn.. and as my office has less than ideal windows… the lab members benefit plant wise.

Excited to share our paper by Raffaella De Pace Saikat Ghosh et al. showing that BORC-dependent transport of lysosomal vesicles into the axon is crucial for the axonal movement of a large cohort of mRNAs, mainly those encoding ribosomal and mitochondrial proteins nature.com/articles/s4159…

We need something similar for RNA 'granule'.

anyone else in the UK suddenly seeing massive delays in lab supplies arriving? we have an ever growing list of items whose predicted shipping date keeps getting pushed back...

Beautiful work- congrats Ezgi Hacisuleyman!

nature.com/articles/s4159…

Thank you Rockefeller University for highlighting our work! Bob Darnell (@[email protected]) Caryn Hale Jin Chen Jonathan Weissman's Lab

DIV 21 hippocampal neurons (a bit overrun by glia)
cyan- SynGAP1
magenta- Map2
grey- beta actin

Occasionally we add some blues and yellows into our palette of greys.

Apple suggested user pic for my office computer… can take the American out of America, not America out of the American?

Absolute respect for the students involved in this
story. It beggars belief that one PI's ego is allowed not only to make day to day lives in the lab a misery, but also risk ruining the careers of lab members

Too Many Labs Run Like This | Science | AAAS science.org/content/blog-p…

Welcome Ezgi Hacisuleyman, Ph.D., who probes how neurons respond to signals, changing in milliseconds! She's invented a way to inventory their RNA and proteins before and after firing.
#neuroscience #RNA #RNA biology #cellbiology #science #brain wertheim.scripps.ufl.edu/2024/03/26/fir…

From commercial antibodies failing to detect SynGAP.. to seeing a sea of SynGAP on dense cultures.

we have a technician position available in my lab (elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…)- we're looking for someone who will work closely with Dr. Rhys Livingstone on a SynGAP Research Fund (SRF) project looking at local synthesis of SynGAP1.

don't hesitate to reach out with any questions!

Join my Imaging Facility!

We're a young and vibrant group and cover a variety of activities including hardware development and image analysis. 🤖📷

Plus we have infinite supply of lab snacks and lasers to play with!
bi.mpg.de/2678133/job_fu…

Heads up! The #MSCA Postdoctoral Fellowships 2024 call opens in April. 🔍 Start your journey early by exploring potential host organisations now and gear up to craft the perfect proposal! 🌟 🎓🔬

More info and opportunities this way ➡️ europa.eu/!KJ8XY7

things are dire but sometimes you get a free jar of honey with your apology 🐝

mRNA profiles across time and space. Fantastic collaboration with Nils Blüthgen lab Charité - Universitätsmedizin Berlin
Max Delbrück Center MDC-BIMSB biorxiv.org/content/10.110…

fluorescence friday:

after countless antibodies tested/tests (and failures)... SynGAP1 (pan, black) in DIV 21 cortical neurons. Magenta DAPI.

perseverance credit to Dr. Rhys Livingstone

If you use Lipofectamine 2000/3000 then you should read this remarkable study to see what it does to your cells. A reminder of the need for controls.