Today we report in Cell our new PE4max and PE5max prime editing systems that we first presented at @CSHLmeetings in August. 1/12 drive.google.com/file/d/1IGiVl7…

Our work developing Repair-seq, a platform for studying #DNArepair processes, and its application to double-strand breaks is out today Cell. Alongside, we release seq.repair, a portal for exploring many, many DNA repair phenotypes! cell.com/cell/fulltext/…

In the latest issue! PE4 and PE5 are efficient and precise prime editing systems with enhanced efficiency of substitution, small insertion, and small deletion prime edits #geneediting #primeediting #sciencetwitter David R. Liu Harvard University Broad Institute bit.ly/2ZsB5gX

Today we share in Nature Protocols detailed strategy and experimental procedures for designing and executing prime editing (and twinPE) experiments in mammalian cells. Congrats Jordan, Alexander Sousa, Peyton, and Peter Chen for this thorough analysis. drive.google.com/file/d/12oIqq5…

Today we share in Nature Reviews Genetics a review of prime editing for precise and versatile genome manipulation. The review covers current prime editing strategies, limitations, recent developments, and applications, including work from 148 publications. 1/5 drive.google.com/file/d/1K4emjR…

Efficient prime editing in two-cell mouse embryos using PEmbryo go.nature.com/483v6g9