Peter Ly(@PeterLyLab) 's Twitter Profileg
Peter Ly

@PeterLyLab

Assistant Professor | Genome Integrity Lab at UT Southwestern Medical Center. We study how chromosomes segregate, break, mutate, and rearrange.

ID:1052279359434678273

linkhttp://thelylab.org calendar_today16-10-2018 19:25:24

1,6K Tweets

1,8K Followers

588 Following

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Isidro Cortes-Ciriano(@isidrolauscher) 's Twitter Profile Photo

Are you a senior postdoc or early career PI interested in the mechanisms underpinning cancer genome complexity? If so, apply to attend the Forbeck Foundation on cancer genomic rearrangements that Peter Ly, Prof. Titia de Lange and I are organising next year in , 👇

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Sophie Dumont(@DumontLab) 's Twitter Profile Photo

Excited to share a preprint! We find that chromosome size-dependent spindle forces impair mammalian mitotic error correction of long chromosomes. Congrats to graduate student Megan K Chong who led this work! With Miquel miquel rosas salvans and Vanna Tran. biorxiv.org/content/10.110…

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Shrabasti Roychoudhury(@ShrabastiRoych1) 's Twitter Profile Photo

📣 To all the Genome instability enthusiasts, application is open for the next cool science jam session for the TRAINEES: Gordon Research Seminar: DNA Damage, Mutation and Cancer,2024. Together with Lindsey Jackson Pale as chairs we are planning an exciting program ⬇️

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Gaëlle Legube lab Chromatin Repair(@LabLegube) 's Twitter Profile Photo

Our paper is out, Bravo and thanks to all the contributors!!👏👏
Take home: after DSB induction, gH2AX domains self-segregate to form a new chromatin compartment, in which some DDR genes also physically relocate to potentiate their expression.
rdcu.be/doT6W

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Peter Ly(@PeterLyLab) 's Twitter Profile Photo

Celebrating 32 wonderful years of the San Diego Branch of the Ludwig Institute for Cancer Research. Had a great time learning about the inspiring history and field-leading discoveries of the branch, as well as catching up with former colleagues and labmates !

Celebrating 32 wonderful years of the San Diego Branch of the Ludwig Institute for Cancer Research. Had a great time learning about the inspiring history and field-leading discoveries of the branch, as well as catching up with former colleagues and labmates !
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Peter Ly(@PeterLyLab) 's Twitter Profile Photo

Had a blast at the @ForbeckForum Scholar Retreat. I am sad that this was my last retreat, but it was an honor to be part of this wonderful foundation over the past 4 years!

Had a blast at the @ForbeckForum Scholar Retreat. I am sad that this was my last retreat, but it was an honor to be part of this wonderful foundation over the past 4 years!
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Roel Verhaak(@roelverhaak) 's Twitter Profile Photo

We developed the ecTag method to visualize ecDNA in live cells (see Yi et al, Cancer Disc 2021). Now, first author (and soon faculty member) Eunhee Yi has put together a detailed guide: sites.google.com/view/ectagmeth….

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Haico van Attikum @haicovanattikum.bsky.social(@haicovanattikum) 's Twitter Profile Photo

We are searching for a highly-motivated postdoc to study a newly-identified DNA repair protein, ZNF384, using state of the art functional genomics and biochemistry approaches. Interested in joining vanattikumlab.org? Apply via the link below:
tinyurl.com/hedwn8nx

We are searching for a highly-motivated postdoc to study a newly-identified DNA repair protein, ZNF384, using state of the art functional genomics and biochemistry approaches. Interested in joining vanattikumlab.org? Apply via the link below: tinyurl.com/hedwn8nx
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VH Oestergaard(@OestergaardLAB) 's Twitter Profile Photo

Happy to share that our short review 'Emerging roles of the CIP2A–TopBP1 complex in genome integrity' by @Ummethum et al is out! academic.oup.com/narcancer/arti…

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Susana Godinho(@godinho_susana) 's Twitter Profile Photo

Guess what?? We have an exciting PhD project fully funded for 4-years 🙌🤩 by the amazing CRUKCOLcentre in collaboration with Sue Hadjur Barts Cancer Institute UCL Cancer Institute. Check it out 👇
colcc.ac.uk/2024-phd-proje…

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Zhao Lab(@WXZhaoLab) 's Twitter Profile Photo

Really happy to share our paper out today @ Molecular Cell, where we elucidate the pivotal roles of BRCA1-BARD1 ligase in not only early DNA end resection but also subsequent stages in homology-directed repair. Congratulations to all the authors!
sciencedirect.com/science/articl…

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Whetstine Lab(@WhetstineLab) 's Twitter Profile Photo

@CEI-FCCC Fox Chase Cancer Center Cell This discovery has major clinical implications in understanding the genesis of extrachromosomal amplifications & associated chromosomal rearrangements, & sheds light on how to therapeutically control the treatment-induced KMT2A amplifications and rearrangements in cancer

@CeiFccc @FoxChaseCancer @CellCellPress This discovery has major clinical implications in understanding the genesis of extrachromosomal amplifications & associated chromosomal rearrangements, & sheds light on how to therapeutically control the treatment-induced KMT2A amplifications and rearrangements in cancer
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Jason Sheltzer(@JSheltzer) 's Twitter Profile Photo

Check out our new review in Trends in Genetics on chromosome engineering to study cancer aneuploidy, where we highlight monumental new advances from McClelland Lab, Teresa Davoli , Alison M. Taylor, Ben-David Lab, Charles Swanton, Glennis Logsdon , and more.
authors.elsevier.com/a/1hr7PcQbJ7X5K

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Amanda Ya(@_AmandaYa) 's Twitter Profile Photo

Sometimes, after scanning coverslips for hours in the dark, you find a weird little cell that reminds you of how cool your research is👩‍🔬

Pictured: a tripolar mitosis where we are able to identify which chromosome is lagging through the use of FISH🔬

Sometimes, after scanning coverslips for hours in the dark, you find a weird little cell that reminds you of how cool your research is👩‍🔬 Pictured: a tripolar mitosis where we are able to identify which chromosome is lagging through the use of FISH🔬#aneuploidy #stemcells
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Nima Mosammaparast(@NimaMLab) 's Twitter Profile Photo

Happy to share our most recent review on how RNA impacts DNA repair. Thanks to Ning Tsao and Mohamed Ashour (NOT) for their work! authors.elsevier.com/a/1hqaT5aisDUB…

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