Peter Ly
@PeterLyLab
Assistant Professor | Genome Integrity Lab at UT Southwestern Medical Center. We study how chromosomes segregate, break, mutate, and rearrange.
ID:1052279359434678273
http://thelylab.org 16-10-2018 19:25:24
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Excited to share a preprint! We find that chromosome size-dependent spindle forces impair mammalian mitotic error correction of long chromosomes. Congrats to graduate student Megan K Chong who led this work! With Miquel miquel rosas salvans and Vanna Tran. biorxiv.org/content/10.110…
📣 To all the Genome instability enthusiasts, application is open for the next cool science jam session for the TRAINEES: Gordon Research Seminar: DNA Damage, Mutation and Cancer,2024. Together with Lindsey Jackson Pale as chairs we are planning an exciting program ⬇️
Great collaboration with The Sung Lab at UTHSCSA
to uncover a key R-loop resolvase, DICER, the only one working on R-loops and NOT on simple DNA-RNA hybrids. Thanks. Arijit Dutta Universidad de Sevilla Asociación Española Contra el Cáncer Agencia Estatal de Investigación European Research Council (ERC) Vencer el Cáncer @csic Conexión Cáncer CSIC
doi.org/10.1016/j.molc…
Our winners from poster session at Cancer Biology Retreat! Justin Engel from Peter Ly, Niki from Malladi Lab - UTSW, Issac from Todd Aguilera MD PhD and Stefanie from Le lab!
Guess what?? We have an exciting PhD project fully funded for 4-years 🙌🤩 by the amazing CRUKCOLcentre in collaboration with Sue Hadjur Barts Cancer Institute UCL Cancer Institute. Check it out 👇
colcc.ac.uk/2024-phd-proje…
@CEI-FCCC Fox Chase Cancer Center Cell This discovery has major clinical implications in understanding the genesis of extrachromosomal amplifications & associated chromosomal rearrangements, & sheds light on how to therapeutically control the treatment-induced KMT2A amplifications and rearrangements in cancer
Check out our new review in Trends in Genetics on chromosome engineering to study cancer aneuploidy, where we highlight monumental new advances from McClelland Lab, Teresa Davoli , Alison M. Taylor, Ben-David Lab, Charles Swanton, Glennis Logsdon , and more.
authors.elsevier.com/a/1hr7PcQbJ7X5K
Sometimes, after scanning coverslips for hours in the dark, you find a weird little cell that reminds you of how cool your research is👩🔬
Pictured: a tripolar mitosis where we are able to identify which chromosome is lagging through the use of FISH🔬 #aneuploidy #stemcells