In this #RPTH original article, authors report on feasibility and acceptability of the AEGIS pilot study:

#anticoagulation #stewardship

@jekurlande Danielle Helminski Sarah K Raymond De Vries J. Joyce Kim Caroline Richardson, MD Geoff Barnes Anticoagulation Forum

Read: rpthjournal.org/article/S2475-…

In this #RPTH original article, Andrew M. Peseski, DO et al report on an epidemiological study comparing #VTE characteristics, risk factors, & outcomes between pts with & without active cancer in a racially diverse population

Duke HemeOnc Fellows Andrea Sitlinger

Read:rpthjournal.org/article/S2475-…

🚨Insights from the #ACTIV -4c trial:

Stratification by age, #Covid_19 severity, D-dimer, & risk scores did not identify a high-risk population that benefits from outpt Apixaban thromboprophylaxis

Lisa Baumann Kreuziger Raj Kasthuri Abdus S Wahed Lana (Bahour) Wahid, MD
Read rpthjournal.org/article/S2475-…

Whoop! So excited and proud for this to be published. What a mammoth effort from everyone involved!

What is the rate of #thrombosis & meningococcal infections in #PNH pts Rx w/ Pegcetacoplan?

Authors report on data from clinical trials & postmarketing settings:
✅similar thrombosis rates to terminal inh
✅No meningoccal infections

Hisakazu Nishimori
Read: rpthjournal.org/article/S2475-…

#RPTH Original Article: Authors report on factors modulating #platelet reactivity from a large population using 5 different assays

Mel Chan 🏳️‍🌈🧪✌️ Florian Thibord Bongani Nkambule Joe Grech (he/him) Zoe Schneider, MPH Dr. Jennifer Huffman Paul Armstrong Tim Warner Andrew Johnson
Read rpthjournal.org/article/S2475-…

Read this thoughtful commentary by jeffrey kline et al, on an #RPTH Original article exploring pregnant individuals counseling needs when ruling out #PE

Commentary: rpthjournal.org/article/S2475-…

Original article: rpthjournal.org/article/S2475-…
Camille Simard Isabelle Malhamé Vicky Tagalakis

In this #RPTH Original article, authors report efficacy and safety analysis of Emicizumab in older people with #hemophilia A from 4 Phase III RCTs

Key point: Outcomes similar to those in the population aged <50 years.

Read here: rpthjournal.org/article/S2475-…

In anticipation of our June 11 webinar on Fibrin Formation & Fibrinolysis Testing in Research, let us know what you think is the right answer🤔:

In your opinion, what is the most reliable method to assess fibrin formation in vitro?

🚨New Webinar Alert🚨Join our June webinar with Valerie Tutwiler on fibrin formation and fibrinolysis testing and research: academy.isth.org/isth/2024/isth…

Wow. How did I miss this paper from RPTH!
- Vaccination in the skin, instead of the muscle, produces antibodies at one-fifth of the dose.
- Vaccination in the skin gave less systemic inflammation than intramuscular vaccination.

New scoping review paper on #Emicizumab #Hemlibra published in ⁦⁦RPTH⁩. rpthjournal.org/article/S2475-…

Excited to present our work of 3 years live, and more so that it is during an #RPTHResearchRecap , which I used to moderate and organize in the past back when I was an RPTH SM-AE!

🦠New study from highlights benefits of intradermal #COVID19 vaccines!

💉 Produces antibodies at 1/5 the dose.
🔥 Less systemic inflammation.
🩸 Lower risk of coagulation.
🌟 Intradermal vaccines may be safer!

rpthjournal.org/article/S2475-…
Astrid van Hylckama

RPTH Research Recap: A machine-learning approach to predict mortality due to immune-mediated TTP x.com/i/broadcasts/1…

How effective are anticoagulants to prevent VTE in #MultipleMyeloma ?

🩸 Rare serious bleeds: 1.4%
📉 Anticoagulants do not increase bleeding risk
🧬 Bleeding risk factors: age, comorbidity, history, hypertension, renal disease

🔎rpthjournal.org/article/S2475-…
Diego Adrianzen-Herrera, MD Pamela Lutsey

A comprehensive review from @guyyoungmd of 97 studies on #Emicizumab for #HemophiliaA shows promising results!
🩸Median annualized bleeding rates: 0.0-1.4
💉Common adverse event: injection-site reactions
🏃‍♂️Significant quality of life benefits
🔗 rpthjournal.org/article/S2475-…

Webinar «A machine learning approach to predict mortality due to immune-mediated thrombotic thrombocytopenic purpura», organizado por ISTH

📅 20 de mayo
⏰ 12:00 ET / 16:00 UTC
👉 streamyard.com/watch/Ffmjdrxu…

Read this State of the Art review on connecting dyslipidemia and impaired fibrinolysis!

First presented at ISTH 2023, this paper reviews current understandings, correlation in different racial and ethnic groups, and summarizes new findings!

Ze Zheng
rpthjournal.org/article/S2475-…

Can ML algorithms help in bleeding risk evaluation in #VTE based on baseline pt variables?

In this #RPTH Original Article authors find that ML algorithms offer no prediction benefit compared to available clinical tools.

perkinslab.ca PhilWellsMD
Read: rpthjournal.org/article/S2475-…