My group has ERC funded PhD positions to study male germ cells maturation. 
For more information and to apply look at: uu.nl/en/organisatio…

The #ShawPrize in #LifeScienceandMedicine 2023 is awarded for groundbreaking work in gene transcription, one of life’s fundamental processes. But what exactly is gene transcription? Pro. #EvaNogales is here to break it down for us.
The Nogales Lab

Pleased to share our latest preprint from the Barford group MRC Laboratory of Molecular Biology the structure of the yeast outer kinetochore bound to microtubules. Many thanks to David Barford, and my co-authors Chris Batters, TomDendooven Jing Yang Ziguo Zhang Alister Burt biorxiv.org/content/10.110…

Phase separation on microtubules: from droplet formation to cellular function? See what Anna Akhmanova and I had to say in response to this question in our new review at
Trends Cell Biology
authors.elsevier.com/sd/article/S09…

Check out our cryoEM result of mRNA editosome in Trypanosoma brucei! Awesome collaboration with Aphasizhev lab from Boston U. Many congrats to Bruce Shiheng Liu⁩ and other coauthors for another wonderful piece of work! science.org/doi/10.1126/sc…

In trypanosomes, gRNA-directed RNA editing restores protein coding capacity of mitochondrial cryptogenes by massive posttranscriptional insertions/deletions of uridines. A new #cryoEM study Science Magazine explores structural basis of this wild process
bit.ly/adg4725

How to assemble the Gene Machine? See a new❄️🔋🔬Science Magazine by Arnaud Vanden Broeck + Sebastian Klinge, from Rockefeller University, on biogenesis of the human large ribosomal subunit bit.ly/adh3892

Join us and get a close 👀 at🍩's. ter.li/vbj3dn

Tubulin nano-code from Gaia Pigino et al! PTMs are localized on a subset of protofilaments in cilia
biorxiv.org/cgi/content/sh…

We wrote a Preview paper “Tektin makes a microtubule a ‘micropillar’” in Cell Cell for two amazing papers of doublet microtubule structures from sperm flagella published by Leung et al. and Zhou et al.
authors.elsevier.com/a/1hIEbL7PXmcgg

Nice work from Phil Bayly, Susan Dutcher and collaborators, using acoustic trapping as an alternative way to confine microswimmers so the can be imaged at high res, including flagellar synchrony in the case of #chlamydomonas .
pnas.org/doi/epdf/10.10…

Check out a recent publication in Cell spearheaded by Jianwei Zeng in the Rui Zhang lab! Great work, Jianwei and Leung et al. You can find the publication here: cell.com/cell/fulltext/…!

Prefer dynein and microtubules? Check this one out, now out in NatureStructMolBiol:

'Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport'

Markus Lab
Jack Zhang Lab
Pengxin Chai
Yue Wang

doi.org/10.1038/s41594…

Comparing the axonemal doublet microtubules from sea urchin (external fertilizer) and bovine (internal fertilizer) sperm revealed evolution and molecular diversity, especially of the tektin bundle

Proteins that play a key role in sperm motility identified using electron microscopy uu.nl/en/news/protei…