How often do you recommend direct immunofluorescence when you see eosinophils tagging at the dermo-epidermal junction. Answer: pretty much always. Nice example of linear C3 in gestational pemphigoid. #dermpath #dermtwitter #SilviPearls #pathology

World class lamellar fibroplasia -- in a melanocytic nevus of a privileged site

Anyone know what these are in this skin biopsy? #dermpath

Question for the #dermpath crews here: when you see a mixed inflammatory pattern ( psoriasiform, interface and dermal peri vascular) with increased dermal plasm cells and endothelial swelling. Your first thought is SYPHILIS!!!! But the IHC stain coming back neg. What’s your call?

Glands ? No! Pseudo- glands from a SCC. Not everything you see is telling you the truth by first glance 😊
Skin, Temple, 65 yo man
#dermpath
Olaleke Folaranmi Lorand Kis Etan Marks, DO David Terrano Marcelasaeblima. Arjun Ramaiya Gonzalo De Toro Silvija Gottesman MD Dermpath_doc_trish

The Eye of Sauron gazing from a warty dyskeratoma

Dermpath_doc_trish Bobbi Pritt, MD Yale Rosen Diego Morales, MD Andrew Kanik Henry YANG Marcelasaeblima. Arjun Ramaiya I found an interesting paper where the authors ran various stains to show different pollen structures. I'm by no means a pollen expert or anything like that, so not sure how much this translates across different species of pollen, but if you have the block it might be interesting…

Hi #PathTwitter 😊! I need some help. Bobbi Pritt, MD Yale Rosen Diego Morales, MD Andrew Kanik - anyone!.
This older female was trimming trees/hedges a few weeks ago and felt something (“foreign body sensation”)in her eye. Any clue what it may be? Left is sclera right photomicrograph.

Let’s add focal cutaneous mucinosis to the list of things that can have basaloid follicular induction. #dermpath #dermatology #pathology #RealLifeDermpath Further reading: PMID: 19542921 and 29293479, both in the Int Soc Dermpath journal.

Dermatosis que hacen figuras perfectas: placas anulares, circinadas, arciformes. Que a la dermatopatología 🔬muestran un patrón psoriasiforme con PAS negativo para estructuras fúngicas.

#myiasis Botfly larvae (dermatobia) infestation. Scalp, travel to Central America #dermpath #dermatology #pathology

Thursday #dermpath special. 😆🔬

In my practice this kind of low-power look on H&E suggests BPDCN until proven otherwise (as it’s so common here), but this time it’s different and HP gives some morphologic clue!

Cutaneous involvement by plasma cell myeloma

See IHC/ISH below.

Without having seen the requisition form, when I placed the slide under the microscope, my first impression was fibroadenoma and I was completely incorrect!
Its a skin biopsy! 🙃
#PathTwitter #dermpath #pathology

Here is another morphologic beauty I would like to share on Earth Day. 😆🔬🌎🌍🌏

I haven’t seen this kind of massive cells in this entity for a while (arrow). Can anybody guess what this #IHCPath might be?

#pathology #dermpath

Here's a nice little glomus tumor (glomangioma) excised from an elbow, composed of a well-circumscribed vascular mass with proliferations of uniform, eosinophilic glomus cells surrounding dilated vessels

#pathology #PathTwitter #dermpath #dermatology #dermtwitter

Nice Monday afternoon fungal nail infection! Has anyone else found microscopic iPhoneography even more of a challenge now there are so many lenses? 😅 #dermpath

Beautiful case. What's your diagnosis? What does this entity arise from?

#pathology #dermpath #dermatology #histology #dermtwitter #meded #medtwitter #pathtwitter #skin #dermatologia

Nice treasure hidden by epidermal hyperplasia.

CHROMOBLASTOMYCOSIS

#path #PathTwitter #dermtwitter #dermatopathology #MedTwitter #infectiousdisease

#RealLifeDermpath : what is Myiasis? Infestation by fly larvae. While we teach our trainees about the exotic Dermatobia (botfly) larva w/ pigmented spines, please note many other flies can cause Myiasis.👀 Musca domestica larva. No travel. From leg of patient. #dermpath #pathology

☀️Morning
❄️Afternoon
Rochester, NY
March 29, 2023
#ROC #RochesterNY #colors #sun #snow #photography #fotografia