2020 we compared generics vs innovator native L-asp x.com/drgauravnarula… Did things get better? 4 generics in prospective open label RCT Tata Memorial Hospital 2>>other 2 But all generics<<innovator! Need for TDM & better quality PHO INDIA SIOP International INPHOG SIOP Global Health Young LMIC SIOP Asia

Read our latest paper about #pediatric CNS tumors in Peru. ✅ Most tumors were diagnosed later than in HIC. ✅ Hydrocephalus was the most common sign at disease presentation that was related to a delayed diagnosis. journals.lww.com/jpho-online/Ab…

World, we have arrived. Congratulations Gaurav Narula MD Rahul Purwar and team. Homegrown CAR-T cells 'cure' 8-year-old's leukemia. timesofindia.indiatimes.com/india/homegrow… Download the TOI app now: timesofindia.onelink.me/mjFd/toisupers…

#CARTcell #India Progress so far- ⏺ Ph I trial over at #TMH Gaurav Narula MD Rahul Purwar - indigenous CAR Tcell safe ⏺ Another trial going on at #NH Dr Sunil Bhat ⏺ Novartis Gilead Sciences CAR Tcell not yet launched in India why ?? ⏺ ⬇️ cost would ⬆️accessibility

We need to talk about...bleomycin. Friend or Foe? - non-haem Fe protein - ?works by free-radicals ➡️ DNA strand break - discovered 1962 by Hamao Umezawa 🇯🇵 - made by Streptomyces verticillus - FDA approved 1972 Read on to see why its use is controversial. #lymphomacontroversies

To kick off the “Generating Evidence From Our Practice And Putting Evidence Into Practice” session at the 2022 St. Global Alliance Convening, Venky introduces the audience to his self-crafted “Cycle of Evidence.” #StJudeGlobal #CompleteTogether

“Nutrition is the most important drug in resource-limited settings,” says Venky. “If we want to bridge the gap between high-income countries and low-income countries, we need to pay attention to malnutrition.” #StJudeGlobal #CompleteTogether #ChildhoodCancer

Great talks snd discussions about research needed for generating evidence in LMIC at St. Jude Research global alliance meeting.

Well said, Venky Well said! St. Jude Research #StJudeGlobal

“If you don't publish, the world won't know what you are doing,” says Venky. “Sometimes, a small article can still change someone's life.” #StJudeGlobal #ComeTogether #ChildhoodCancer

💯 We totally agree! 🎗 Nutrition is an essential pillar for the life and treatment of #ChildhoodCancer patients and survivors. 🙌 Thank you for sharing these strong and powerful words, Daniel Bastardo Blanco, PhD

Save the date! Int Childhood Cancer Day is on February 15. Together with Childhood Cancer International our message in 2023 is "Better Survival is achievable#throughtheirhands"which focuses on paying tribute to the families and caregivers’ positive impact on the lives of children with cancer.

Sex disparity in pediatric cancer care in India. sciencedirect.com/science/articl… Hospital and population-based registry data for 30000 pediatric cancer patients. First of its kind study from India. ❌Bias towards diagnosis in boys More in North India. Sameer Bakhshi

Highlights the issues faced by girl child with cancer in India. More boys compared to girls ❌ in private centres than in centres providing subsidised treatment (p<0·0001) ❌ haematological malignancies than those with solid malignancies (p<0·0001)

❌ residing 100 km or further from the hospital than those within 100 km ❌those living in rural areas than those living in urban areas (p=0·0006). ❌The Male to Female ratio of 514 children who underwent HSCT was 2·81 (95% CI 2·32–3·43) in favour of boys. INPHOG PHO INDIA

SIOP International SIOP Global Health Young LMIC SIOP Global Health Young LMIC Ministry of Health AIIMS, New Delhi Cancer Institute (WIA), Chennai ISMPO Ind J Med Ped Oncology Pediatric Hematology Oncology Journal The Lancet Oncology

PHO chapter of India is super proud of Venky and his achievement. SIOP Asia SIOP Asia 2023 SIOP Global Health SIOP International SIOP-Africa Young SIOP SIOPE 🎗️ Pediatric Hematology Oncology Journal

Reduction in chemo dose intensity by 25% and adding Rituximab improves survival in pediatric high grade B Non Hodgkins Lymphoma in resource limited settings. onlinelibrary.wiley.com/doi/full/10.10… Outcomes comparable to high income countries. A 25% improvement in survival compared to past.

✅ Malnutrition and MDR Gram negative bacteria associated with increased mortality in pediatric B NHL in LMICs. ✅ A less dose intense protocol reduces toxicity and treatment related mortality and allows for giving chemo on time thereby reducing relapses.

✅ Rituximab compensates for reduction in dose intensity #oncology #cancer #PediatricOncology