ShorterLab(@ShorterLab) 's Twitter Profileg
ShorterLab

@ShorterLab

Countering deleterious phase transitions in ALS/FTD, PD, AD, and related disorders @Penn @PennMedicine @bb_upenn @BMBGGUPENN @PGGUPenn @PennNGG @CAMBUpenn

ID:474088050

linkhttp://www.med.upenn.edu/shorterlab/index.html calendar_today25-01-2012 16:55:19

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ShorterLab(@ShorterLab) 's Twitter Profile Photo

Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry | PNAS pnas.org/doi/10.1073/pn…

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Kresten Lindorff-Larsen(@LindorffLarsen) 's Twitter Profile Photo

Very happy to share work led by Sören von Bülow on prediction of phase separation propensities of disordered proteins from sequence

We combined active learning and coarse-grained simulations to develop a machine learning model for quantitative predictions of IDR phase separation

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Coleman Lab(@Lab_Coleman) 's Twitter Profile Photo

Why is it so hard to feel successful in research? And how can we change that? New blog post in this week’s ‘Science Without Anguish’. sciencewithoutanguish.com

Why is it so hard to feel successful in research? And how can we change that? New blog post in this week’s ‘Science Without Anguish’. sciencewithoutanguish.com
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ShorterLab(@ShorterLab) 's Twitter Profile Photo

Proteasome gene expression is controlled by coordinated functions of multiple transcription factors: rupress.org/jcb/article/22…

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ShorterLab(@ShorterLab) 's Twitter Profile Photo

De novo design of proteins housing excitonically coupled chlorophyll special pairs: nature.com/articles/s4158…

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ShorterLab(@ShorterLab) 's Twitter Profile Photo

The role of Matrin-3 in physiology and its dysregulation in disease, interesting review from Jackrel Lab Members: portlandpress.com/biochemsoctran…

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ShorterLab(@ShorterLab) 's Twitter Profile Photo

Size Scaling of Condensates in Multicomponent Phase Separation | Journal of the American Chemical Society pubs.acs.org/doi/full/10.10…

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Olivia Rifai(@olivia_rifai) 's Twitter Profile Photo

Our new pre-print characterising neuropathological correlates of behavioural dysfunction in ALS, particularly protein aggregation and ferritin accumulation in the amygdala, is out now - by GregoryLab and our wider collaborative team.

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Charlotte Fare(@CharlotteFare) 's Twitter Profile Photo

Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy link.springer.com/article/10.100…

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ShorterLab(@ShorterLab) 's Twitter Profile Photo

Direct observation of fluorescent proteins in gels: a rapid, cost-efficient and quantitative alternative to immunoblotting biorxiv.org/content/10.110…

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ShorterLab(@ShorterLab) 's Twitter Profile Photo

Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer’s disease: nature.com/articles/s4146…

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ShorterLab(@ShorterLab) 's Twitter Profile Photo

The Folding of Germ Granule mRNAs Controls Intermolecular Base Pairing in Germ Granules and Maintains Normal Fly Development biorxiv.org/content/10.110…

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ShorterLab(@ShorterLab) 's Twitter Profile Photo

De novo variants in the non-coding spliceosomal snRNA gene RNU4-2 are a frequent cause of syndromic neurodevelopmental disorders medrxiv.org/content/10.110…

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ShorterLab(@ShorterLab) 's Twitter Profile Photo

The diversity of SNCA transcripts in neurons, and its impact on antisense oligonucleotide therapeutics biorxiv.org/content/10.110…

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Rothstein Lab(@Rothstein_Lab) 's Twitter Profile Photo

Failure of C9orf72 sense repeat-targeting antisense oligonucleotides: lessons learned and the path forward academic.oup.com/brain/article/…

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ShorterLab(@ShorterLab) 's Twitter Profile Photo

Mutations in the U4 snRNA gene RNU4-2 cause one of the most prevalent monogenic neurodevelopmental disorders: nature.com/articles/s4159…

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