I’m not an oncologist and a lot these studies are intimidating due to the hard names of drugs. But. If I’m diagnosed with cancer, and a doc recommends a Rx, I’m googling it along with “Vinay Prasad”. Incredibly important work for patients and society. Kudos John Arnold

Follow the Drug Development Letter ❗️👇🙂

Why you shouldn't get a full body MRI
@zdogg interviews me on why it is a bad idea
youtube.com/watch?v=FzFT-K…

Everything you need to know about Sotorasib
Will interest anyone interested in drug development
Consider subscribing for more
developdrugs.substack.com/p/sotorasib-kr…

Just out in the Drug Development Letter, I summarize arguments in the two papers on Sotorasib One by
Timothée Olivier, MD
and the other by Tito Fojo
Dr Amol Akhade
developdrugs.substack.com/p/sotorasib-kr…

Assessing patient risk, benefit, and outcomes in drug development: A decade of ramucirumab clinical trials onlinelibrary.wiley.com/doi/10.1002/ca… via Vinay Prasad MD MPH et al

Time 100 Health Care is a deeply problematic list
I go through specific examples where nominees embodied the opposite of what they are lauded for
Walid Gellad
Jay Bhattacharya Martin Kulldorff Marty Makary MD, MPH

open.substack.com/pub/vinayprasa…

A banger of an episode to bring the VPDZ Show back to life. Vinay Prasad MD MPH Dr. Zubin Damania #VPDZ

open.spotify.com/episode/727u81…

Drug makers make so much money from such marginal drugs, they are now incentivized to run portfolios of low value trials

This misuses patient participants and results in unacceptable harms

IRBs should become stronger
drive.google.com/file/d/10w7Gvs…

What does it say about the US cancer system that a drug that only improves survival 1.5 months in 3 tumor types can be given to 10,000 research participants, in many cases, based on a lark

The conclusion is....

Two episodes about economics, two more about Israel. One about affirmative action and another about dying well. Anything related to health researcher Vinay Prasad and blogger @TylerCowen: @econtalker shares the surprising list of fav episodes from 2023: ow.ly/MI4O50RqKui

Talked with Dr. Zubin Damania about the death of his father. Here is our discussion.

youtu.be/YTSCtjqUDo4?si…