how did long DNA molecules - 100 times longer than those usually sequenced in cancer - help us solve a paradox about BRCA deficiency? read all about in our paper, out in nature today nature.com/articles/s4158… 👇🧵 1/

This is just the beginning for prime editing screens! It has been a truly fun collaboration with @jshendure and Alice Berger. Funding from National Human Genome Research Institute, Center for the Multiplex Assessment of Phenotype and IGVF

Big advance in variant characterization right here! Flo’s work shows prime editing can be used for large scale positive selection screens - and in doing so identifies some novel osimertinib resistance variants! Thanks for the great collaboration Jay Shendure Lea Starita

The same awesome ACS Research Scholar Grant that has launched the careers of thousands of cancer researchers, but now more money starting with the Fall 2023 review cycle!

Not my PhD, but this describes my postdoc 💯

Thanks LungCancerAmerica! So grateful for the support and community!

Thank you to IN for the last four years as the inaugural Innovators Network endowed chair. Congrats to Dr. Shadman for being names the next recipient!

Great funding opportunity!

When former President Obama was asked to share his most important career advice for young people, he replied...

'Just learn how to get stuff done.'

Hey you! Are you a PhD (or equivalent) student within 2 years of graduation or who have graduated in the last year? Join us Fred Hutchinson Cancer Center to explore careers in #immunology , #oncology and #datasciences . Food, lodging and travel covered! Apply by July 15: fredhutch.org/en/events/prim…

Time to move beyond the serial 'whack-a-mole' paradigm of monotherapy for single genetic alterations that activate MAPK signaling? With CGP & advances in drug dev, we can hit multiple independent oncogenic pathways simultaneously.
bit.ly/46mBVtR
pubmed.ncbi.nlm.nih.gov/37182602/

Nice collection of #Bioinformatics tutorials and seminar from the National Cancer Institute including introduction to unix, #rstats , Bioconductor and single cell annotation

bioinformatics.ccr.cancer.gov/btep/btep-vide…

We're pleased to announce a groundbreaking research partnership with Lung Cancer Research Foundation to fund $2 million in ALK-positive lung cancer research over the next 3 years. This award will support research focused on ALK-positive non-small cell lung cancer (NSCLC).

alkpositive.org/blog/2023/6/15…

🎉 Ready to elevate your #LungCancer #Research skills & career?

Join us for #EGFR Summit in collab w/@egfrresisters & @CEC_onc

Submit your abstracts by Aug 18 & gain valuable career insights ➡️ce.ceconcepts.com/EGFR23

Jill Feldman Ivy Elkins Zosia Piotrowska
#LCSM #EGFR #NSCLC

What a fantastic meeting so far! Can’t wait for day 2!

Thanks very much for a very fun conference with lots of new connections made and knowledge gained!

One of the most important things taught in grad school is that this, and not the 'scientific method' taught in high school science classes, is how a lot of the best science gets done

Spread the word: We are looking for a new director of the National Human Genome Research Institute sequencing center! I work very closely with this group and the staff are absolutely fantastic (nisc.nih.gov). Please reach out to me if you have any questions! Ad: genome.gov/careers-traini… (1/3)

1. Excited to share our new paper in nature! With over 1000 tumors analyzed by scRNA-seq, we provide a systematic pan-cancer characterization of transcriptional intra-tumor heterogeneity (ITH)
nature.com/articles/s4158…

Why inhibit only one KRAS mutant when you can inhibit multiple KRAS alterations at the same time.

Our pan-KRAS inhibitor paper is out.

nature.com/articles/s4158…