The authors here have studied uEVs with cell line derived EVs besides soluble proteins and identified temporally stable urine proteins ..an extensive anlaysis

An exciting study lead by talented PhD student Elnaz Khalili Samani revealed cryoEM structures of native protein assemblies from brain lysate of a rat model of Alzheimer's disease. Collaboration with JoAnne McLaurin and Thomas Kislinger. doi.org/10.1101/2024.0…

A speaker you won’t want to miss! Dr. Thomas Kislinger, Senior Scientist at Princess Margaret Cancer Centre and Professor at the University of Toronto. An expert in proteomics, his research advances cancer biology through novel methodologies and liquid biopsy signatures.

We are thrilled to share our latest research on "Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells" published in Nature Medicine, led by former PhD student Dr. Chirayu Chokshi Chirayu Chokshi McMaster Health Sciences #glioblastoma #McMaster rdcu.be/dPLrp

Love this cover art by student Linda Berg Luecke on this month's issue of Journal of Proteome Research ACS for Authors #MyACSCover Veneer is a tool to standardize and improve how cell surface proteomics data are interpreted and distributed. pubs.acs.org/doi/10.1021/ac…

The Weeks Lab UW–Madison Biochem is hiring at all levels! Broadly, our lab uses engineered enzymes to decipher cellular signaling to advance biological discovery and therapeutic development. If this sounds exciting to you, please reach out! Reposts appreciated. 🧪weekslaboratory.org

Functional CRISPR screens in GBM patient identifies the PTP4A-ROBO1 axis as a driver of tumorigenicity and enriched ROBO1 expression in recurrent GBM that can be targeted via ROBO1-directed CAR T cell therapy Sheila Singh Brain Tumour Lab Centre for Discovery in Cancer Research Chirayu Chokshi nature.com/articles/s4159…

✨ Join this virtual symposium of ANZSEV, 22 Aug 2024, targeted at Early Career Researchers! 🌐 Asia/Pacific timezone, free registration, welcome to all 📝 Full programme and more info here: buff.ly/3MgGlcV Student Network on EVs @ISEVcomms

IMSC2024

The Proteogenomics of Prostate Cancer Radioresistance pubmed.ncbi.nlm.nih.gov/39166898/

Recently published: The Proteogenomics of #ProstateCancer #Radioresistance, by Roni Haas et al. bit.ly/3MjpkhY Beth Neilsen Danny Vesprini Amar Kishan Melvin LK CHUA Thomas Kislinger #openaccess

We have a new preprint showcasing work led by Emmajay and TVeth that uses a real-time library search to classify precursor ions as potential N- or O-glycopeptides for on-the-fly decisions abt fragmentation. We call this approach Autonomous Dissociation-type Selection (ADS)

moPepGen: Rapid and Comprehensive Identification of Non-canonical Peptides - This study presents *moPepGen*, a groundbreaking graph-based algorithm designed to rapidly generate non-canonical peptides in linear time across multiple technologies and species. - Key innovation:

moPepGen: Rapid and Comprehensive Identification of Non-canonical Peptides biorxiv.org/content/10.110… --- #proteomics #prot-preprint