New @JORSpine report shows how compressive loading & swelling speeds up cryoprotectant delivery in IVDs; ⏫ high cell viability after cryopreservation. Big step for full disc transplantation & research! See: doi.org/10.1002/jsp2.1… ORS Spine Section #RegenMed #Spine

New @JORSpine report shows 3-month #romosozumab treatment improves regional bone mineral density & biomechanical parameters in elderly patients with osteoporosis undergoing spine surgery. See full study: doi.org/10.1002/jsp2.1… ORS Spine Section #spine #bone

New report in @JORSpine: Study highlights the effectiveness of FPLA as a flexible support material for TE-IVDs. 🌟 FPLA cages outperformed PLA, maintaining disc height and supporting hydrated tissue formation. See: doi.org/10.1002/jsp2.1… #Spine #RegenMed ORS Spine Section

New @JORSpine #insilico study examines different #GDF5 doses on hNP cells. 🌟 Findings: 0.25 & 1 mg doses could be effective for matrix synthesis?! Key insights for #RegenMed? Explore the study: doi.org/10.1002/jsp2.1… #Orthopedics #SpinalCare ORS Spine Section ORS Preclinical Models Section

New report in @JORSpine uncovers collagen damage in AF tissues of DDD patients with CHP staining. 🔍 Results show strong correlations in degradation markers, offering new insights into DDD pathology. Check it out: doi.org/10.1002/jsp2.1… #SpineCare #RegenMed ORS Spine Section

New review @JORSpine explores #perlecan's role in IVD, highlighting its critical functions in tissue protection and remodeling. 🧬 Perlecan's mechanotransduction and ECM interactions offer new therapeutic targets. See all >> doi.org/10.1002/jsp2.1… #Biomaterials ORS Spine Section

Out in @JORSpine: Research uncovers important molecular markers and immune cell changes in hypertrophic ligamentum flavum. Highlights include #TGFβ and #TNF pathways. Valuable insights for understanding spinal fibrosis. See the details: doi.org/10.1002/jsp2.1… ORS Spine Section

Recent @JORSpine article examines the impact of axial compression and distraction on cervical facets under flexion. Results show increased facet strains with higher compression, indicating a potential rise in fracture risk. doi.org/10.1002/jsp2.1… #Biomechanics ORS Spine Section

New work @JORSpine shows model to predict annulus fibrosus fiber orientations from disc geometry alone. 🌟 Results match experimental data in bovine and human discs, highlighting important fiber asymmetries. Explore the study: doi.org/10.1002/jsp2.1… ORS Spine Section

Study in @JORSpine reveals how ligamentum flavum degeneration contributes to spinal stenosis; key changes in tissue structure, composition, and biomechanics. 🧬 Learn more: doi.org/10.1002/jsp2.1… #SpineHealth #Orthopedics

Applications are open to join ISSLS! Be part of a global network of spine research leaders advancing #LumbarSpine care. 🌍 Deadline: September 1st❗️ Learn more about all the benefits and how to apply: 🔗issls.org/membership #SpineResearch #JoinISSLS #RetweetMe

New @JORSpine review examines discogenic #backpain and explores how biomolecular therapies could target pain pathways beyond IVD degeneration showing the need for therapies addressing chronic LBP. Learn more: doi.org/10.1002/jsp2.1… ORS Spine Section #SpineHealth #BioMolecular

New @JORSpine review on #Curcumin's potential to mitigate spinal cord injury complications by modulating key inflammatory pathways like #Nrf2, #NFkB, and #TGFβ. 🌿 Could curcumin be the future of SCI treatment? Find out more: doi.org/10.1002/jsp2.1…

New @JORSpine: A new U-Net model automates 3D disc segmentation from spine MRIs, matching manual accuracy and streamlining analysis across diverse ages and degeneration levels. #AI #MRI #MedicalImaging ORS Spine Section doi.org/10.1002/jsp2.7…

🔧 New study @JORSpine: A #DeepLearning model accurately identifies pedicle screw brands from spine radiographs, aiding preoperative planning in revision #spinesurgery. The AP+Lateral ensemble model achieved 94% accuracy, matching experienced surgeons! 🔗doi.org/10.1002/jsp2.7…

New in @JORSpine: A dual-model #AI system for #LDH patients automates muscle segmentation and fatty infiltration (FI) annotation on #MRI, showing shows high accuracy in paraspinal muscle and FI assessment compared to traditional methods! 🔗doi.org/10.1002/jsp2.7…