In the latest issue! Past, present, and future of CRISPR genome editing technologies dlvr.it/T3hXDN

Here we demonstrate that OrthoRep can be employed to evolve genome editors - Congrats to Yanik and many thanks to all collaborators - rdcu.be/dAEnD

Coming soon! Latsis Symposium on Genome Engineering #Zurich #switzerland June 13-14. latsis-genome-editing.ethz.ch Great lineup Treutlein lab Ben Kleinstiver Raffaella Di Micco Sek Kathiresan MD Janice Chen Charles Gersbach Cejka Lab Teresa Davoli Jolanda van Leeuwen Cereseto Lab Anna Obenauf Prisca Liberali

Registration and abstract submission (deadline May 31, 2024) are open for the 2024 Latsis Symposium on "#Genome and #Transcriptome #Engineering", which will be held on June 13 and 14, 2024, ETH Zurich. latsis-genome-editing.ethz.ch Jacob Corn Martin Jinek Randall Platt Gerald Schwank

Join me at the Latsis Symposium on Genome Engineering #Zurich #switzerland June 13-14! Register now at latsis-genome-editing.ethz.ch/registration.h… Treutlein lab Ben Kleinstiver Raffaella Di Micco Sek Kathiresan MD Janice Chen Charles Gersbach Cejka Lab Teresa Davoli Jolanda van Leeuwen Cereseto Lab Anna Obenauf Prisca Liberali

Join us at the Latsis Symposium on Genome and Transcriptome Engineering organized by Martin Jinek Randall Platt Jacob Corn and Gerald Schwank, with lots of great speakers from academia and industry! 🧬 #Zurich #Switzerland June 13-14. Register at: latsis-genome-editing.ethz.ch/registration.h…

Our latest research on a highly unexpected mechanism of antiviral immunity by reverse transcriptase-based defense systems is now live on bioRxiv! A remarkable work of science, and art, led by the talented Stephen Tang. Check out his thread to learn more! biorxiv.org/content/10.110…

Are you (also) a defense system aficionado? Then don't miss the beauty of the DdmDE defense system from pandemic V. cholerae. Outstanding work by our collaborators Luuk Luuk Loeff from Martin Jinek lab who solved the CryoEM structure & molecular mechanism🥳 tinyurl.com/58nv4k96

Just one week until the Latsis Symposium on Genome Engineering #Zurich Free registration at latsis-genome-editing.ethz.ch/registration.h… Treutlein lab Ben Kleinstiver Raffaella Di Micco Sek Kathiresan MD Janice Chen Charles Gersbach Cejka Lab Teresa Davoli Jolanda van Leeuwen Cereseto Lab Anna Obenauf Prisca Liberali

Congratulations to the fabulous (but Twitterless) Kenny Jungfer on passing his PhD thesis defence with flying colours last Friday! #ProudPI

Our paper on the molecular mechanism of plasmid elimination by the DdmDE defense system is now out in Science Magazine! A great collaboration between the Martin Jinek lab at UZH Science and @Mblokesch at EPFL. science.org/doi/10.1126/sc… A🧵

Our paper exploring the effect of chromatin on prime editing and diverse pegRNA designs was published today! 👨‍💻🧬🎉 rdcu.be/dLu0f pridict.it UZH Science Nature Biotechnology Gerald Schwank Krauthammer Lab Bas van Steensel lab 🧵

If you want to know the outcome of your prime editing experiment before you even conducted the experiment, visit pridict.it Congrats to Nicolas and many thanks to all collaborators Krauthammer Lab Bas van Steensel lab

Paper out today: “RNA-guided RNA Silencing by an Asgard archaeal Argonaute”. A wonderful, multidisciplinary project co-led with Daan C. Swarts Joo_Lab, spearheaded by Carolien Bastiaanssen Pilar B U Kijun Kim giadafinocchio & Yanlei Feng. nature.com/articles/s4146… Nature Communications

Check out our latest paper showing that HLTF removes Cas9 from DNA, explaining phenotypic differences when using the two Cas9 nickase variants. Important for gene editing! Thanks to Giordano Reginato & Rosaria and Martin Jinek Taekjip Ha andre nussenzweig lab nature.com/articles/s4146…

I am deeply honoured to have been elected as EMBO member. My thanks go to past and present lab members, colleagues and collaborators, who all helped to make this happen! embo.org/press-releases…