Interested in metallo-β-lactamases and their inhibitors? Some interesting findings and conclusions in our latest manuscript led by group members Nicola Wade and @KamaleddinT. Check out the pre-print that just dropped at ChemRxiv! doi.org/10.26434/chemr…

Here's a new video about our group's research on "Universiteit van Nederland". universiteitvannederland.nl/colleges-en/wh…

Me waiting as my TLC runs

Fresh Monday morning preprint drop! Total Synthesis of the Brevicidine and Laterocidine Family of Lipopeptide Antibiotics. A great collaboration with the group of Stephen Cochrane (Stephen Cochrane, Ross Ballantine) and our own Karol Al Ayed (@AyedKarol). doi.org/10.26434/chemr…

Note to master student interns: this is a great way to end one’s time in our group 😁. Excellent work in both the lab and the cupcake making department by the talented Floor

Courtesy of group member Ned Buijs - the scariest pumpkin an organic chemist can ever see 😜

Had the pleasure of hearing Carolyn Bertozzi speak yesterday at Leiden University. I especially enjoyed learning about the excellently named post-translational protein modification known as "Neddylation". I guess my next field of study has been determined for me.

E. faecium colonies visualised using SEM in the presence and absence of my new antibiotic. We're hoping to have my research story that accompanies this data published in the next few months.

I've just had my first first author paper accepted at ChemBioChem on my improved synthesis of the antibiotic bacitracin A! This allows for the preparation of analogues that can harness bacitracin's unique mechanism of action and fight AMR. …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…

Attention peptide chemists in the Netherlands! Be aware that a bad batch of "peptide synthesis grade" DMF is in circulation. Appears to be highly amine contaminated and has caused us much frustration recently. Feel free to DM me if you'd like to know the vendor and batch number.

excited to receive the PhD thesis of Ned Buijs on nextgen Bacitracins. Another great thesis in the tradition of the Nathaniel Martin lab LeidenBiology. Defense on 20 December.

Thank you very much to our PhD and postdoc organizers of the inaugural Leiden Early Drug Discovery & Development (LED3) PhD/postdoc Symposium #LED3Symposium (Charlotte Hijmans, Sophie Wintermans, Rik Remmers, Ned Buijs , mata ). You did amazing work organizing this event!