Why (and how) we need to professionalize neuroscience By Jakob Voigts thetransmitter.org/systems-neuros…

When is a dopamine transient not a dopamine transient? When it's a photoconversion artifact from blue-light illumination of an mApple based sensor! Comment on 'Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation' biorxiv.org/content/10.110…

Excited to share this new paper from my group! Jennifer Zachry and M. Gunes Kutlu show that D1 and D2 MSNs in the nucleus accumbens do not have opposing actions and neither population signals reward. Instead, D1 MSNs respond to salient stimuli and D2 MSNs to prediction errors

Cutting it a bit fine, but it's that time again: The Spike's review of the year in neuroscience 2023: A Review of the Year in Neuroscience link.medium.com/7lJ0d4aTWFb Enjoy! including Dud{man,Lab}🇺🇦 Sandeep Robert Datta nic tritsch 🇺🇦 🏳️‍🌈 #BLM Jesse Goldberg Wei Ji Ma and many more

nic tritsch 🇺🇦 🏳️‍🌈 #BLM Thank you for bringing the awareness to the community. The photoactivation phenomenon of mApple-based red fluorescent sensors should be handled with caution when using these sensors. We also discussed this issue in our latest paper on GRAB-DA sensors.

1/3 It's important to note that most mApple-based biosensors exhibit blue light-illuminated photoactivation, and proper controls (e.g. mutant-sensor or biosensor-only controls) should be included in combined use with blue-light optogenetics or dual-color recording.

New paper alert! Our work on the extra-amygdalar panic circuit has been published Nature Neuroscience. Congrats to co-first authors Sukjae Joshua Kang and Jonghyun Kim along with all co-authors involved. nature.com/articles/s4159… 🧵(1/n)

Is one of your new year's resolution to attend one of the best Neuro Circuits meetings? Then consider registering for Ascona Circuits this upcoming fall. Deadline is April 30, 2024

Curious how the brain changes to help one avoid a bully? Happy to share our new work published today in nature. Three excellent scientists Takuya Osakada, Rongzhen Yan, and Yiwen Jiang jointly pushed the project to its finish line. rdcu.be/dwPrr

Excited about our long-brewing paper exploring dynamics in multi-regional neural circuits in a delayed movement task. Driven by@esthersselva, Yi Liu, and including Jennifer Colonell, Nuo Li and Shaul Druckmann and others (the MAP collaboration): cell.com/cell/fulltext/… (1/7)

Excited to share new long-brewing work from the lab! Is the world feeling…..at bit too aggressive? Maybe it would be good to just take it down a notch? We have thoughts about this! rdcu.be/dyqAn

Congrats Anya Krok, MD PhD for matching to NYU Grossman School of Medicine’s psychiatry residency program (research track)! Very proud of you!!

How does the brain select what to consolidate during sleep? New in @sciencemagazine , our work (science.org/doi/10.1126/sc…) sheds light on the brain's mechanism for selective memory consolidation. 🧵👇1/n

Do you think about dopamine ramps? If so, we hope that this story would be interesting to you and demonstrate that an underappreciated experimental variable has a strong influence on when they appear in a task. Work led by Joey Floeder and helped by Huijeong Jeong Ali Mohebi

The Tritsch Lab is looking to hire adventurous postdocs to study (1) how neuromodulators like dopamine and acetylcholine interact to promote learning and action, and (2) how the basal ganglia control the vigor of skilled movements in Parkinson's disease. DM me if interested!

Wrapping up another wonderful 2 week in woods hole teaching with Matt van der Meer, Jess Cardin and Stephen Cowen as part of NS&B. Great science, students and colleagues in surreal setting