We are happy to announce that our study on imputation of ancient human genomes is now published in Nature Communications: nature.com/articles/s4146… Thank you to all co-authors! Simone Rubinacci Eduardo Amorim 🏳️‍🌈🇧🇷 Diana Ivette @siko76 Hannes Larsson AnnaSapfo Malaspinas Olivier Delaneau Dept of Computational Biology, Uni Lausanne SIB

So excited to share our recent work! 🎉 Just released 2 innovative tools in Nature Genetics: nature.com/articles/s4158… nature.com/articles/s4158… Huge applause to my great team of brilliant researchers who made this possible! Stay tuned for deeper insights.

🎉 Thrilled to share a major career update! 🎉 I'm honored to join the Regeneron Genetics Center as Director in Statistical Genetics. Sad to bid farewell to Lausanne, but eager to contribute to the groundbreaking research done at the RGC! 🧬🖥️📊

Happy to announce the release of 200k UK Biobank WGS phased with SHAPEIT5, together with cutting-edge imputation pipelines. Relevant links: - Processing: biobank.ndph.ox.ac.uk/showcase/refer… - Access: biobank.ndph.ox.ac.uk/showcase/field… - Pipelines: srubinacci.gitbook.io/uk-biobank-imp… More details to come!

Since our inception, large-scale human genome sequencing has fueled our discovery, and needless to say, we’ve been busy. As we count down to a decade of team RGC, join us in reflecting on our sequencing milestones that helped us amass the world’s most diverse genetic database. 🌎

It’s the second anniversary of the UK Biobank Research Analysis Platform (UKB-RAP)! We’ve collected our highlights from the past year in this video & in the below thread: youtu.be/E523eRY6XwY

📢 Excited to share our latest preprint on UK Biobank WGS and non-coding rare variant associations! 🧵 Olivier Delaneau Dept of Computational Biology, Uni Lausanne #UKB #NonCoding #RareVariants Study breakdown below: ⬇️

📢 New preprint alert! Refining SHAPEIT5 haplotypes using whole genome sequencing reads. 🧬On #UKbiobank, it confirms a fascinating trend-de novo mutations are more often paternally inherited. 👏 to Rick Wertenbroek and Olivier Delaneau for this smart work! biorxiv.org/cgi/content/sh…

Whole genome sequencing of half-a-million UK biobank participants medrxiv.org/content/10.110…

We are happy to announce that our work on the impact of post-mortem damage and contamination on imputation performance in ancient DNA is now out on bioRxiv! biorxiv.org/content/10.110… Olivier Delaneau Simone Rubinacci AnnaSapfo Malaspinas Dept of Computational Biology, Uni Lausanne SIB

lundbeckfonden.com/themes/ancient… Four articles in nature uncover the genetic traces and geographical origins of diseases such as multiple sclerosis and Alzheimer’s based on ancient human DNA. More than 175 researchers from across the world, led by Eske Willerslev, participated in the

We're thrilled to welcome Dr. Nina Mars (Nina Mars), Dr. Arafath (Rafa) Najumudeen (Arafath (Rafa) Najumudeen) and Dr. Simone Rubinacci (Simone Rubinacci) as the newest FIMM-EMBL Group Leaders HiLIFE_Helsinki University of Helsinki! helsinki.fi/en/hilife-hels…

Delighted to share our paper "Assessing the impact of post‑mortem damage and contamination on imputation performance in ancient DNA" supervised by Barbara now out in Scientific Reports! Simone Rubinacci Olivier Delaneau AnnaSapfo Malaspinas Dept of Computational Biology, Uni Lausanne SIB ➡️More details here: nature.com/articles/s4159…

New paper introducing RESHAPE, a method simulating genomes of hypothetical descendants that can be used as reference panels safeguarding against re-identification threats. Read more: nature.com/articles/s4358…. Great work done by Théo Cavinato!