Vignesh Packiam, MD (@vigneshpackiam) 's Twitter Profile
Vignesh Packiam, MD

@vigneshpackiam

Associate Prof @RutgersCancer @rwjurology | Previously at @UIowa_Urology | Alum @MayoClinic @Uro_Onc, @UChicagoUro, @PittMedAlum, @UWBadgers| Views my own

ID: 2220627830

linkhttps://www.cinj.org/vignesh-t-packiam-md calendar_today29-11-2013 01:45:51

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Vignesh Packiam, MD (@vigneshpackiam) 's Twitter Profile Photo

Data for Gem/Doce for low volume (<30%, no LVI) micropapillary variant NMIBC. As per recently updated AUA guidelines, repeat TURBT (w/ blue light IMO) is particularly important for variant histologies Rutgers Cancer Institute Saum Ghodoussipour Ian McElree Bladder Cancer Advocacy Network pubmed.ncbi.nlm.nih.gov/38796357/

Data for Gem/Doce for low volume (&lt;30%, no LVI) micropapillary variant NMIBC. As per recently updated AUA guidelines, repeat TURBT (w/ blue light IMO) is particularly important for variant histologies

<a href="/RutgersCancer/">Rutgers Cancer Institute</a> <a href="/saumyg/">Saum Ghodoussipour</a> <a href="/IanMcelree/">Ian McElree</a> <a href="/BladderCancerUS/">Bladder Cancer Advocacy Network</a>

pubmed.ncbi.nlm.nih.gov/38796357/
Ashish M. Kamat, MD, MBBS (@urodocash) 's Twitter Profile Photo

The IBCG Quick Guide to Non-Muscle Invasive Bladder Cancer (NMIBC) Bladder Cancer Quick Reference Sheet summarizes essential details on diagnosis, treatment options, and follow-up for NMIBC all in one convenient place #AUA24 #EAU24 #IBCG24 #ASCO24 Designed by Amanda Myers

The IBCG Quick Guide to Non-Muscle Invasive Bladder Cancer (NMIBC)

Bladder Cancer Quick Reference Sheet summarizes essential details on diagnosis, treatment options, and follow-up for NMIBC all in one convenient place  #AUA24 #EAU24 #IBCG24 #ASCO24

Designed by <a href="/AmandaMyersMD/">Amanda Myers</a>
Lars Dyrskjøt (@ldyrskjot) 's Twitter Profile Photo

Our latest paper on ctDNA detection using WGS is now published in European Urology. This WGS-based approach simplifies clinical workflows by eliminating the need for personalized assays. Read the paper here : doi.org/10.1016/j.euru…

Our latest paper on ctDNA detection using WGS is now published in <a href="/EuropeanUrology/">European Urology</a>.  This WGS-based approach simplifies clinical workflows by eliminating the need for personalized assays. Read the paper here : doi.org/10.1016/j.euru…
Madhuri Koti (@canimmun) 's Twitter Profile Photo

A nice recent report on BCG strain differences and outcomes in patients with IR/HR NMIBC. pubmed.ncbi.nlm.nih.gov/37827948/ Remains to be resolved!!

A nice recent report on BCG strain differences and outcomes in patients with IR/HR NMIBC.  pubmed.ncbi.nlm.nih.gov/37827948/
Remains to be resolved!!
Roger Li (@urogerlimd) 's Twitter Profile Photo

Final results of #CORE001 trial out now Nature Medicine (1/14) 35 pts with BCG-UR CIS treated w/ Creto + pembro 👉12mo CR (per RBB) = 57.1% (ITT) 👉24mo CR = 54% *(Auth Corr) 👉No patient progressed to MIBC 👉No synergistic toxicity Gary Steinberg nature.com/articles/s4159…

Final results of #CORE001 trial out now <a href="/NatureMedicine/">Nature Medicine</a> (1/14)

35 pts with BCG-UR CIS treated w/ Creto + pembro

👉12mo CR (per RBB) = 57.1% (ITT)
👉24mo CR = 54% *(Auth Corr)
👉No patient progressed to MIBC
👉No synergistic toxicity

<a href="/garysteinbergmd/">Gary Steinberg</a>

nature.com/articles/s4159…
Vignesh Packiam, MD (@vigneshpackiam) 's Twitter Profile Photo

Great study and interview on Gem/Doce for BCG-unresponsive NMIBC!! Inexpensive (~100x cheaper!) and highly effective (50% 2 year RFS) alternative to newer FDA approved agents Main limitation to Gem/Doce is retrospective - so its fantastic for our pts to have studies like these

UroToday.com (@urotoday) 's Twitter Profile Photo

Sequential gemcitabine and docetaxel show promise for intermediate-risk #NMIBC. Vignesh Packiam, MD Rutgers RWJ Urology joins Sam S. Chang MD, MBA Vanderbilt Urology to discuss the emerging role of intravesical gem/doce for treating #NMIBC. #WatchNow > bit.ly/4aeVRiU

Sequential gemcitabine and docetaxel show promise for intermediate-risk #NMIBC. <a href="/VigneshPackiam/">Vignesh Packiam, MD</a> <a href="/rwjurology/">Rutgers RWJ Urology</a> joins <a href="/UroCancerMD/">Sam S. Chang MD, MBA</a> <a href="/VUMCurology/">Vanderbilt Urology</a> to discuss the emerging role of intravesical gem/doce for treating #NMIBC. #WatchNow &gt; bit.ly/4aeVRiU
Ashish M. Kamat, MD, MBBS (@urodocash) 's Twitter Profile Photo

It's encouraging to see the lively discussion this has sparked. To clarify: we are not advocating for rescue BCG for all BCGU patients. What we are emphasizing is that if BCG were evaluated today in a single-arm registration study, it could likely be ‘approved’. While we must

It's encouraging to see the lively discussion this has sparked. To clarify: we are not advocating for rescue BCG for all BCGU patients.

What we are emphasizing is that if BCG were evaluated today in a single-arm registration study, it could likely be ‘approved’. 

While we must
Sina Sobhani (@sinas2020) 's Twitter Profile Photo

Thrilled to share our latest publication on salvage HIFU for prostate cancer post-radiation failure! This review highlights patient selection criteria, promising disease control, and favorable outcomes compared to radical treatments tinyurl.com/2fpr3b2x Amir Lebastchi, MD

Thrilled to share our latest publication on salvage HIFU for prostate cancer post-radiation failure! This review highlights patient selection criteria, promising disease control, and favorable outcomes compared to radical treatments
tinyurl.com/2fpr3b2x
<a href="/AmirLebastchi/">Amir Lebastchi, MD</a>
Rutgers Cancer Institute (@rutgerscancer) 's Twitter Profile Photo

Watch Rutgers Cancer Institute's Dr. Vignesh Packiam Vignesh Packiam, MD weigh multiple recent studies that explore the efficacy of gemcitabine/docetaxel as a frontline therapy for upper tract urothelial #carcinoma. guoncologynow.com/post/sequentia… RWJBarnabas #UroOnc #Chemotherapy #KidneyCancer

Toni Choueiri, MD (@drchoueiri) 's Twitter Profile Photo

Updated National Comprehensive Cancer Network (NCCN) guidelines (1.2025) are in, with some major changes for systemic therapies: 1) Ipi+Nivo is now a preferred regimen in fav-risk ccRCC 2) Len+Pem/Cabo+Nivo are now preferred regimens for non-clear cell RCC 3) Adjuvant Pembro is now Category 1 KidneyCAN

Updated <a href="/NCCN/">National Comprehensive Cancer Network (NCCN)</a> guidelines (1.2025) are in, with some major changes for systemic therapies:
1) Ipi+Nivo is now a preferred regimen in fav-risk ccRCC  2) Len+Pem/Cabo+Nivo are now preferred regimens for non-clear cell RCC  
3) Adjuvant Pembro is now Category 1 

<a href="/kidneycan/">KidneyCAN</a>
GU Oncology Now (@guoncologynow) 's Twitter Profile Photo

📺 #ICYMI: Vignesh Packiam, MD of Rutgers Cancer Institute, and KATIE MURRAY of NYU Langone Urology, weigh multiple recent studies that explore the efficacy of #gemcitabine/#docetaxel as a frontline therapy for #UTUC. 👉 Watch Now: buff.ly/4d25DH5

Laura Bukavina (@laurabukavinamd) 's Twitter Profile Photo

What an incredible team effort showcasing a daily reality: over 25% of #BladderCancer pts encounter mental health care barriers >urgent need for accessible programs. Despite progress in med coverage, mental health care remains out of reach for many #Oncology #MentalHealthMatters

What an incredible team effort showcasing a daily reality: over 25% of #BladderCancer pts encounter mental health care barriers &gt;urgent need for accessible programs. Despite progress in med coverage, mental health care remains out of reach for many #Oncology #MentalHealthMatters
JAMA (@jama_current) 's Twitter Profile Photo

Narrative review explores how to manage use of DOACs—apixaban, rivaroxaban, edoxaban, and dabigatran—in patients undergoing surgical and nonsurgical procedures to decrease risks of bleeding and thromboembolism. ja.ma/4fIm1hL

Narrative review explores how to manage use of DOACs—apixaban, rivaroxaban, edoxaban, and dabigatran—in patients undergoing surgical and nonsurgical procedures to decrease risks of bleeding and thromboembolism. ja.ma/4fIm1hL
UroToday.com (@urotoday) 's Twitter Profile Photo

Sequential gemcitabine and docetaxel show promise for intermediate-risk #NMIBC. Vignesh Packiam, MD Rutgers RWJ Urology joins Sam S. Chang MD, MBA Vanderbilt Urology to discuss the emerging role of intravesical gem/doce for treating #NMIBC. #WatchNow > bit.ly/4aeVRiU

Sequential gemcitabine and docetaxel show promise for intermediate-risk #NMIBC. <a href="/VigneshPackiam/">Vignesh Packiam, MD</a> <a href="/rwjurology/">Rutgers RWJ Urology</a> joins <a href="/UroCancerMD/">Sam S. Chang MD, MBA</a> <a href="/VUMCurology/">Vanderbilt Urology</a> to discuss the emerging role of intravesical gem/doce for treating #NMIBC. #WatchNow &gt; bit.ly/4aeVRiU