Twitter Beğeni Hilesi

Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment dlvr.it/T9N1S4

CXCL13 shows up prominently in T cells in autoimmune tissues and tumors. Human Tfh and Tph cells produce lots of CXCL13, yet its regulation is pretty unclear. With beautiful CRISPR screens by Jaehyuk Choi, Calvin Law, we found a few key factors... nature.com/articles/s4158…

A new Science study establishes a platform for integrating and elucidating CD4+ T cell diversity and genetic risk of immune-mediated diseases. Learn more: scim.ag/7Fm

Excited to see the last chapter of my #PhD published today Nature Immunology. This was a perfect collaboration with my friend Pratiksha Thakore. We analyzed the chromatin landscape of Th17 cells and identified BACH2 as an important regulator. nature.com/articles/s4159…

REVIEW Nature Immunology Caitlin Zebley, MD PhD T cell dysfunction and therapeutic intervention in cancer nature.com/articles/s4159…

So excited! Hot off the press in nature We present a human autoimmune organoid model capable of mimicking celiac disease. | driven by Antonio Santos! | Calvin Kuo Lab Stanford Medicine nature.com/articles/s4158…

Sharing our latest paper by Arti Medhavy & Vicki Athanasopoulos. Underscores the value of: i) discovery of rare gene variants in children with ambiguous diagnoses of autoimmunity; ii) collaboration between The Crick, John Curtin School of Medical Research, ANU, & Shanghai Renji Hospital - Nan Shen nature.com/articles/s4159…

TGFβ inhibits development of intestinal TH17-dervied cells that induce cancerous transformation of intestinal epithelium not via IL-17, but in KLF6/T-BET/IFN-γ-dependent manner Nature Immunology Valentin Thevin julien C. Marie nature.com/articles/s4159…

Did you know that B cells reside in your nose and secrete antibodies? Learn more in our new study by Jingjing Liu Jingjing, published in nature. rdcu.be/dPR2m 🧵

Synergy between LAG-3 and PD-1 in subversion of CD8 T cell effector function Cell Vignali Lab E. John Wherry Tony Cillo, PhD Tullia Bruno, PhD cell.com/cell/fulltext/… cell.com/cell/fulltext/… cell.com/cell/fulltext/… cell.com/cell/fulltext/…

Perhaps a slight detour from the dream of publishing a novel, but still exciting nonetheless! Our new Methods in Molecular Biology edition on Memory B-Cells is out now…

Human organoids with an autologous tissue-resident immune compartment | Nature nature.com/articles/s4158…

Finally out: Characterizing T cell specific responses to vaccine and infection in HLA-DPB1*04-restricted patients across 4 time points. Thank you Philip Mudd and Ali Ellebedy for inviting me into this amazing data set. Paper: nature.com/articles/s4159…

Two new papers report the specificity & differentiation dynamics of human LN TFH cells after flu or COVID vaccines. The flu paper is a collab. between my lab (stefan.schattgen ) & Ali Ellebedy, while the COVID was led by Ali, Philip Mudd, and Nick Borcherding-a 🧵nature.com/articles/s4159…

Discovered 30 years ago, CD40L antagonists are proving to be powerful autoimmune drugs Science Magazine science.org/doi/10.1126/sc…

New from us In the 2024 Current Opinion in Immunology: Tumour Immunology section, Benjamin Broomfield and I contrast the stem-like T cell niche in LN and TME to understand how to enhance vaccination and immunotherapy Many thanks to Stefani Spranger for the invite sciencedirect.com/science/articl…

Dear Cluster members and associated scientists, the abstract submission for the Cluster Science Days 2024 is open! Please submit your abstract by September 26th. We are thrilled to feature your interesting research and can't wait to offer you an exciting program.

Great collaborative project, glad to be part of it!

One week to apply!!! We are looking for a postdoc to complete the newly established Mucosal Immunology group. Great position supported by the Immunosensation excellence cluster! euraxess.ec.europa.eu/jobs/259925

We are hiring! Looking for a #postdoc to join the team in the Nowak Lab to focus on chemical biology in cells and recombinant systems. Excited about protein degradation, small molecule proximity? get in touch! #TPD #InducedProximity #ChemicalBiology nowak-lab.com