This BJD study determines a 1.3% change in body surface area is the minimal important difference for #vitiligo and impact is 7 times greater when the face is affected: ow.ly/me6050PchMv
Anti-IL-36 receptor treatment with imsidolimab shows promise for generalized pustular psoriasis, with 6 of 8 patients meeting the primary endpoint of this open label study in this month's BJD: ow.ly/55af50PchMY
In this month's BJD, Dutch BioDay registry study demonstrates successful dupilumab interval prolongation in more than 80% of patients in remission, with cost savings of millions of Euros: ow.ly/PrS050PchIZ
In this month's BJD, defective cathepsin Z affects EGFR expression and causes autosomal dominant palmoplantar keratoderma, raising the possibility of topical therapy with EGFR inhibitors: ow.ly/kjrG50PchJU
In this BJD, analysis of BABIR data shows #psoriasis patients given adalimumab are twice as likely to be clear or nearly clear and are less likely to discontinue treatment vs methotrexate: ow.ly/JU0c50PchKE
Phase IIa RCT of amlitelimab, an anti-OX40 ligand monoclonal antibody, provides initial safety and efficacy data for moderate to severe #AtopicDermatitis: rebrand.ly/iznl5f3
Survival from cutaneous #squamouscellcarcinoma is linked to the abundance of B cells in the peritumoral stroma, which is prognostic, even in immunocompetent patients: rebrand.ly/gne1xrk
Score severity bands and minimal important change for the key RECAP instrument measuring long term #AtopicDermatitis control now available: rebrand.ly/l4l59mc
Data from Taiwan show that Stevens–Johnson syndrome and toxic epidermal necrolysis on average reduce life expectancy by more than 9 years: rebrand.ly/6rdx8hy
Randomized control trial of adjuvant immunoadsorption in pemphigus did not show clear clinical benefit and there was a higher rate of severe infections. Check it out! academic.oup.com/bjd/article/19…
Stigma due to #vitiligo is higher in those with facial involvement, depression and darker skin tones and mild, moderate and severe stigma are now defined with the PUSH-D scale: academic.oup.com/bjd/article-ab…
Cooling agents acting via transient receptor potential melastatin 8 (TRPM8) agonism can reduce #itch, as demonstrated in a trial of a topical TRPM8 agonist: academic.oup.com/bjd/article-ab…
Dermatology services can be supported by #ArtificialIntelligence, however there are multiple ethical considerations as highlighted in this BJD review: academic.oup.com/bjd/article-ab…
Korean study demonstrates risk of death with Behcet disease is 1.28 X the general population and is 2.66 X greater in the 1st year after diagnosis: academic.oup.com/bjd/article-ab…
Results of the phase IIa RCT of Izuforant, a selective oral histamine 4 receptor (H4R) antagonist, for cholinergic #urticaria are in this months’ BJD academic.oup.com/bjd/article-ab…