For all the T cell receptor sequencers out there, the latest version of our analysis pipeline Decombinator 5.0 is live, and now on PiPy for greater ease of installtion ! Thanks to Matt Cowley for a huge amount of work ! pypi.org/project/decomb…

People who lack the immune protein TNF can still fight infection go.nature.com/4cN6CtQ

CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes: Immunity cell.com/immunity/abstr…

Microbiota-induced plastic T cells enhance immune control of antigen-sharing tumors | bioRxiv biorxiv.org/content/10.110…

Excited for our #ECI2024 satellite symposium "A New Era of T Cell Research" tomorrow 9:30 AM in Wicklow Hall 2A. Look forward to welcoming our fantastic speakers! ENLIGHT-TEN+ Tcelleurope

Sepsis induces dysfunction and exhaustion-like phenotypes in liver NK cells and ILC1 bmcimmunol.biomedcentral.com/articles/10.11…

REVIEW Role of lymph node NK cells in anti-tumor immunity mdpi.com/2227-9059/12/8…

Excited to see our story showing that the #stressresponse regulator #HSF1 modulates NK cell anti-tumour immunity out in ⁦Nature Cell Biology⁩. Thanks to fantastic work with ⁦Nikos Kourtis⁩ ⁦Iannis Aifantis⁩ and team ⁦NYU Langone Health⁩ 🧵👇 nature.com/articles/s4155…

Epigenetic reactivation of transposable elements induces tumor-enriched antigens in glioblastoma but also some in proliferating nontumor cells Nature Genetics Ting Wang Albert H. Kim Nakul Shah Yonghao Liang nature.com/articles/s4158…

In July, scientists announced that HIV had been eliminated from a seventh person after a stem-cell transplant. But how close are we to a cure for the virus — or a vaccine? go.nature.com/4e7RKau

The immune system of trans men reveals how hormones shape immunity nature Petter Brodin Lakshmikanth Tadepally Fabian Sardh Rikard Forlin Camila Rosat Consiglio nature.com/articles/d4158… nature.com/articles/s4158…

new out in Nature. A beautiful study : nature.com/articles/s4158…

'Mechanisms that clear mutations drive field cancerization in mammary tissue' nature.com/articles/s4158…

Excellent review from mariangela russo Bardelli Lab discussing our current understanding of drug-tolerant persister cells in cancer. nature.com/articles/s4156…

Clinical research in the UK is wild 😳 What takes months and a dozen emails in Germany can be years, hundreds of emails, and many meetings in the UK. Urgent reform is needed—thanks for calling out this issue so poignantly!

Beautiful paper in @ScienMagazine from Miriam Merad, MD, PhD & co on aged immune microenvironment, TAMs reprogramming and its impact on cancer progression and recurrence science.org/doi/10.1126/sc…

Part 2 of what I assume is a marvel-like series of papers atlasing cancers with ever increasing expenditure on ATAC: science.org/doi/10.1126/sc…

Achieving optical transparency in live animals with absorbing molecules | ⁦Science Magazine⁩ “…The addition of tartrazine was able to make the skin of a live rodent temporarily transparent..” science.org/doi/10.1126/sc…

#ItIsAKindOfMagic! Zihao Ou HongLab Mark Brongersma &co show Science Magazine that tissue transparency can be achieved in live animals utilizing a common food dye, allowing the “visualization of (…) deep-seated structures and activities”! science.org/doi/10.1126/sc…

Complex relationship between whole body metabolism, NK cell homing, NK cell metabolism and anti tumour responses Nice new study from Joseph Sun Lab Fasting reshapes tissue-specific niches to improve NK cell-mediated anti-tumor immunity cell.com/immunity/abstr…