Delighted to collaborate on this excellent work led by J. Weiss Vineet Raghu Kaavya Paruchuri Michael Lu Mass General Heart using deep learning of widely used chest X-rays to augment current paradigms for statin allocation in primary prevention acpjournals.org/doi/10.7326/M2… Annals of Int Med

We are happy to share that today, Rick Slayman, our first patient to ever receive a genetically edited pig kidney transplant, has been discharged from the hospital. He is recovering well and will continue to recuperate at home with his family.

1/7 🔍 Selective Use (a 🧵): Our latest study, published in Radiology: Cardiothoracic Imaging, evaluated the selective addition of CT Fractional Flow Reserve (CT-FFR) to Coronary CT Angiography (CTA) to identify patients who might benefit from further evaluation/revascularization.

Radiology: Cardiothoracic Imaging Angelo Takigami Praveen Ranganath Reece J. Goiffon, MD, PhD Vinit Baliyan BorekFoldyna Nina Meyersohn Sandeep Hedgire Brian with the Good Dictations MGH Cardiovascular Imaging Research Center Mass General Imaging 2/7 📊 We analyzed 2,985 elective & acute patients who underwent CTA during the initiation of CT-FFR to our multisite academic clinical service. 292 analyses were requested, at CTA readers’ discretion, based on a perceived benefit (i.e., a potential change in management)

Radiology: Cardiothoracic Imaging Angelo Takigami Praveen Ranganath Reece J. Goiffon, MD, PhD Vinit Baliyan BorekFoldyna Nina Meyersohn Sandeep Hedgire Brian with the Good Dictations MGH Cardiovascular Imaging Research Center Mass General Imaging 3/7💡Why Selective Use? Not all patients warrant CT-FFR analysis, which comes at a significant added cost; our service thus opted to utilize it selectively. We most commonly requested for those with potential but not definite anatomically significant stenoses (CAD-RADS ≥3).

Radiology: Cardiothoracic Imaging Angelo Takigami Praveen Ranganath Reece J. Goiffon, MD, PhD Vinit Baliyan BorekFoldyna Nina Meyersohn Sandeep Hedgire Brian with the Good Dictations MGH Cardiovascular Imaging Research Center Mass General Imaging 4/7📈CAD-RADS Scores: Referrals for CT-FFR analysis were predominantly among patients with CAD-RADS scores of 3 (moderate stenosis), accounting for 73.6% of referrals.

Radiology: Cardiothoracic Imaging Angelo Takigami Praveen Ranganath Reece J. Goiffon, MD, PhD Vinit Baliyan BorekFoldyna Nina Meyersohn Sandeep Hedgire Brian with the Good Dictations MGH Cardiovascular Imaging Research Center Mass General Imaging 5/7🚨Benefits: The adoption of CT-FFR was associated with ‍⬇️ in invasive procedures—with invasive coronary angiography (ICA) and percutaneous coronary intervention (PCI) rates dropping to 25.5% and 21.1%, compared with 74.5% and 78.9%, respectively, in those without CT-FFR.

Radiology: Cardiothoracic Imaging Angelo Takigami Praveen Ranganath Reece J. Goiffon, MD, PhD Vinit Baliyan BorekFoldyna Nina Meyersohn Sandeep Hedgire Brian with the Good Dictations MGH Cardiovascular Imaging Research Center Mass General Imaging 6/7 ❤️ A Novel Twist: Our dual-source CTA scans were all successfully conducted without HR control, ensuring quality images across all HRs with a very low rejection rate. We do this carefully; all exams are monitored and nitroglycerin prep is used unless contraindicated.

Radiology: Cardiothoracic Imaging Angelo Takigami Praveen Ranganath Reece J. Goiffon, MD, PhD Vinit Baliyan BorekFoldyna Nina Meyersohn Sandeep Hedgire Brian with the Good Dictations MGH Cardiovascular Imaging Research Center Mass General Imaging 7/7🏥 Why It Matters: CTA is a mainstay in CAD due to its high NPV, and the addition of CT-FFR to enhance PPV proves most valuable when it might alter management. Our “selective use” strategy, awaiting CTA interpretation to decide on CT-FFR, confirms its efficacy in our practice

CT-FFR Informs Need for Invasive Artery Treatment Learn more ➡️ bit.ly/3vPjnoz Mangun Randhawa MGH Cardiovascular Imaging Research Center @mghimaging #RadNews #RadEd #CardiacImaging #CT #CTA

Excited to share our study showing that exercise helps heart health in part by acting through the brain. By strengthening the prefrontal cortex, exercise cuts stress signals…which cuts heart disease events. jacc.org/doi/10.1016/j.…

Amazing grand rounds today by one and only Dr Andrew D. Choi AI in CCTA Brian with the Good Dictations Sandeep Hedgire Nina Meyersohn MGH Radiology Chiefs Ron Blankstein Cian McCarthy Vinit Baliyan MGH Cardiovascular Imaging Research Center BorekFoldyna Giselle A. Suero Abreu, MD PhD Mass General Heart MGH Cardiology Fellows Heart_SCCT

Energized to serve as Visiting Professor at Mass General Imaging MGH Radiology Chiefs @circ_mgh this year! With #YesCCT now front line in guidelines, the field is just getting started - #AI/ML, #PlaqueImaging, prevention, education, expanding access, policy & new plaque trials are the new

Congratulations to Ahmed Tawakol @circ_mgh Mass General Heart and zahifayad on the new PubMed publication of the exciting study: "Effect of Stress-Related Neural Pathways on the Cardiovascular Benefit of Physical Activity." Read the full article here: pubmed.ncbi.nlm.nih.gov/38631773/

MGH Cardiovascular Imaging Research Center ML group in one frame at #SAIL2024 poster session. Forever grateful for the mentorship and guidance of Vineet Raghu & Michael Lu. If you’re around & interested in using #AI-based imaging #biomarkers to gauge #PrecisionMedicine , come check out our work at number 28!

10-year ASCVD risk prediction leads to older individuals being prioritized for statins missing opportunities for earlier risk recognition & prevention. Our work led by Sarah Urbut uses genetics & dynamic risk factor trajectories toward intersecting risk *early.*

In this paper on stress & CVD, we find a novel association between disruptions in the uncinate fasciculus and carotid atherosclerotic burden. Grateful to Ahmed Tawakol zahifayad for this opportunity and to Dave Mandy van Leent for all the help! academic.oup.com/eurheartj/arti…

Congrats Maria Khalil MD & Hui Chong Lau your work on Imaging in the heart-brain axis 🧠🌟📸 Read more here: doi.org/10.1016/j.nucl… MassGeneral News Mass General Heart Mass General Research Institute Mass General Imaging MGH Cardiology Fellows

Honored to work on this review of molecular imaging evaluating the mechanistic interplay of the heart-brain axis under various stressful and diseased conditions — and to publish my artwork! Journal of Nuclear Cardiology MGH Cardiovascular Imaging Research Center Mass General Heart MGH Cardiology Fellows Mass General Imaging doi.org/10.1016/j.nucl…

We had the pleasure to present our findings on the impact of air pollution in different risk groups, an analysis led by Isabel Langenbach. The results might affect management of patients at higher CV risk. Thanks to Ritu Thamman MD for a great discussion. #SCCT2024 MGH Cardiovascular Imaging Research Center Heart_SCCT