unexpected discovery of TSG101 requirement for PARylation and PAR-dependent NF-kB activation!

Excited to share our most recent publication Cell Stem Cell. Unexpectedly, we found that hematopoietic stem cells act as antigen presenting cells! Antigen presentation safeguards the integrity of the stem cell pool and prevents the onset of leukemias (1/8).authors.elsevier.com/c/1f1286tu0CiG…

I’m very excited to share my first, first author research paper with Sherry Zhang! Vignali Lab Nature Immunology nature.com/articles/s4159…

Delighted to share our story out in Cancer Cell! Incredible amount of work led by Julia Belk and Winnie Yao, and wonderful collaborations with many close colleagues Santosh Vardhana Julia Carnevale Marson Lab Mackall Lab cell.com/cancer-cell/fu…

10 amazing websites that cost you nothing, but will save you hundreds of hours of your life:

"I am grateful for my weaknesses, as they make me humbler." At her lowest moment, this industry scientist found strength in weakness. Read her story in this week's #ScienceWorkingLife. fcld.ly/mfi4ha7

BRCA1/2-mutierte #Krebszellen überleben Chemo- und Strahlentherapie oft. Ein Team um #mdcBerlin-Forscher Claus Scheidereit schafft nun die Grundlage, damit gezieltere #Medikamente entwickelt werden können. #Brustkrebs The EMBO Journal Ahmet Bugra Tufan mdc-berlin.de/de/news/press/…

My PhD paper is finally out The EMBO Journal. Special thanks to our brilliant collaborators at FMP Berlin and Max Delbrück Center respectively. embopress.org/doi/full/10.15… Also special thanks to the journalists who made a press release about our study. mdc-berlin.de/news/press/kee…

BRCA1/2-mutated #CancerCells often survive chemo- and radiotherapy. A team led by #mdcBerlin researcher Claus Scheidereit has now paved the way for the development of more targeted drugs. FMP Berlin The EMBO Journal EMBO Ahmet Bugra Tufan #BreastCancer More: mdc-berlin.de/news/press/kee…

An unlikely new activator of #DNAdamage-induced #NFkB signaling and #PARP1 #PARylation: Claus Scheidereit Ahmet Bugra Tufan et al Max Delbrück Center reveal new #ESCRT-independent function of #TSG101 embopress.org/doi/10.15252/e…

Boğaziçi kayyımlığı tarafından üniversitedeki görevimden uzaklaştırılıyorum. Elbette hukuksuzca ve etik dışı uygulamalar neticesinde. Dava süreci sonunda geri döneceğim görevime şimdilik bir ara vermek zorunda kalacağım. Detaylar şu şekilde:

I ask for your help to support this Turkey Earthquake Fund gofundme.com/f/xh8d5t-turke… that will directly help affected families in the region. Thanks everyone who reached out during these difficult times, truly appreciate and will never forget your support ❤️ Please share this 🙏

Two massive earthquakes hit southeastern part of Turkey, including our hometown Hatay. My wife lost almost half of her close family. I lost several people from my family and friends. I cannot express my feelings. We no longer have a home to return to and we are devastated. +

Two horrible earthquakes effected more than 10 cities in turkey including my hometown. Millions have been effected, lost their lifes, houses, their families. You can help them by supporting (links below) and sharing it with more #turkeyearthquake

Dear academic colleagues, if you have any Turkish (& Syrian) students, please reach out to them, ask them how they r doing & consider extending/canceling their deadlines (if there is any). No matter which part of the country they r from they r most probably shaken to the core. +

We are talking about two major earthquakes that affected 10 cities, with a total population of 15 million. Even if they don't have immediate losses they most probably lost acquaintances or know someone who lost someone. Please be considerate.

21 yıldır yurt dışındayım. Dün üniversite bölüm toplantısında millet kakara kikiri yaparken kendimi çok yabancı hissettim, burada ne işim var diye düşünüp durdum.

Congrats Ahmet Bugra Tufan

Finally, the paper that covers most of my work from my PhD has been published in Molecular Oncology . In this paper, we are investigating the role of interferon regulatory factor 4 (IRF4) in melanoma cells. (1/) febs.onlinelibrary.wiley.com/doi/10.1002/18…

Interferon regulatory factor 4 modulates epigenetic silencing and cancer-critical pathways in melanoma cells ➡️buff.ly/4b5BCV7 🥼Ulduz Sobhiafshar Tolga Emre Cansu Yerinde Elif Nur Firat-Karalar #IRF4 #Melanocytes #Epigenetics