In this study, interferon-γ was found to play a large role in the pathogenesis of APS-1. Results were confirmed in studies in animals and led to a trial of ruxolitinib in five patients, who had dramatic responses. Read the full study results: nej.md/4bXoKkG

And now—with the help of amazing collaborators Penn Medicine —we can convert the toxic TREX1 protein (dominant, truncated TREX1 mutant) into the full-length TREX1 using a modified CRISPR approach. The next challenge is optimizing delivery to the blood vessel wall, but we believe

Cryptosporidium is a major cause of diarrheal disease worldwide. Ian Cohn Boris Striepen ChrisHunter et al engineer transgenic C. parvum to express MHCII-restricted model antigens & dissect priming & effector functions in parasite-specific CD4+ T cells hubs.la/Q02zfV7t0

Congratulations ChrisHunter !!!

#cytokineBracket2024 Only 1 week left to cast your votes for the best cytokine! IL-9 vs IL-5 remains tight; IL-15 gaining on IL-12. 2nd round begins July 17. No signups needed, 1 vote per device. International Cytokine & Interferon Society (ICIS) polltab.com/bracket-poll/n…

Discovery of the first IFN-binding protein in herpes viruses reported - Viral modulation of type II interferon increases T cell adhesion and virus spread signals.cytokinesociety.org/2024/07/15/ifn… via International Cytokine & Interferon Society (ICIS)

Results are in #cytokineBracket2024. IL-9 lost out to IL-5 by A SINGLE VOTE! Round 2 begins - Scan the QR Code below: signals.cytokinesociety.org/2024/07/15/632… via International Cytokine & Interferon Society (ICIS) @

Executive Director, Adaptive Immune Tolerance, Immune Therapeutics at Moderna in Cambridge, USA modernatx.wd1.myworkdayjobs.com/M_tx/job/Cambr… Kate Jeffrey

Executive Director, Adaptive Immune Tolerance, Immune Therapeutics Moderna Kate Jeffrey cytokinesociety.org/job/moderna-ca… via @httpstwittercomCytokineSociety

🥳A nice day to celebrate all the Rosalind Franklin Society Award winners🏅 with full anthology released today: rosalindfranklinsociety.org/rfs-awards-in-… Thank u RFS for honouring our JournalJICR publication + thank u JICR (Ray), everyone involved & our funders too 🙏 International Cytokine & Interferon Society (ICIS) Dept of Immunology @ UofM Canadian Society for Immunology

Congratulations to Amir Shamshirian who has received an International #Cytokine & #Interferon Society (ICIS)-Pfizer Junior Investigator Award for Most Promising #Research Presentation. International Cytokine & Interferon Society (ICIS) Pfizer Inc.

Don't miss his talk at #cytokines2024! Amir Shamshirian

SIGNALS+ VOLUME 12 NUMBER 15: #Cytokines2024 Alerts, Member Publication of Interest & New Investigator to Watch Chaoran Li signals.cytokinesociety.org/?hash=64a9d5b

Sarah Gaffen (@SLG1717) is a professor at PittRheum. Her lab explores the biological function of IL-17 and its receptor in the context of fungal host defense and #autoimmunity. Lucie Van Emmenis spoke with Sarah for our latest #PeopleAndIdeas interview: hubs.la/Q02LK9WN0

Join us for the joint Cytokines and KAI 2024 in Seoul, So. Korea. Register by October 7 at Cytokines2024.org

Semi-finals of Cytokine Bracket are LIVE! It's IL-1alpha/beta vs. IL-4 and IL-17 vs. IFNlambda. Great representation of distinct cytokine families, innate & adaptive immunity. Voting open for 2 wks - no signup needed, vote 1x per device. International Cytokine & Interferon Society (ICIS) polltab.com/bracket-poll/n…

Don't miss this inspiring interview to ICIS president Sarah Gaffen (Gaffen Lab 17 (Dr. Sarah Gaffen)) by Lucie Van Emmenis 😉