#PhysicianScientist Development:
The National MD-PhD Program Outcomes Study: career paths followed by Black and Hispanic graduates: buff.ly/4dKozLF

Penn Medicine Albert Einstein College of Medicine - Official

#Cover : Cross-species single-cell analysis uncovers the immunopathological mechanisms associated with IgA nephropathy progression: buff.ly/4a8MG3p

#Image : recruitment of bone marrow–derived immune cells, especially macrophages, that infiltrate into kidney tissue.

Myosin folding boosts solubility in cardiac muscle sarcomeres: buff.ly/4diyckm

University of Vermont
#Cardiology #MuscleBiology

Evaluating immunotherapeutic outcomes in triple-negative breast cancer with a cholesterol radiotracer in mice: buff.ly/3y0NY3d
Gary D Luker MD Michigan Medicine
#Immunology #Oncology

#ClinicalMedicine :
Outpatient #COVID_19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial: buff.ly/3Wn4VPo
David J Sullivan Sabra Klein Johns Hopkins Bloomberg School of Public Health

P2Y13 receptor deficiency favors adipose tissue lipolysis and worsens insulin resistance and fatty liver disease buff.ly/3UEQMMa
Inserm
#Hepatology #Metabolism

HIPK2 C-terminal domain inhibits NF-κB signaling and renal inflammation in kidney injury: buff.ly/3JDesKH

John Cijiang He Icahn School of Medicine at Mount Sinai
#Nephrology

Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models: buff.ly/4aTi47m

long nguyen Yong Loo Lin School of Medicine
#Aging #Metabolism

Natural antibodies drive type 2 immunity in response to damage-associated molecular patterns: buff.ly/4bk1aP8
Claudia Jakubzick Geisel School of Medicine at Dartmouth
#Immunology

Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction: buff.ly/4aWDS1F
Kyoto University
#Ophthalmology #StemCells

Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia: buff.ly/3w4Te5k
University of Cincinnati
#Oncology #Therapeutics

#ClinicalMedicine : Integrated plasma proteomics identifies tuberculosis-specific diagnostic biomarkers: buff.ly/3Uc5EjK
University of Southampton
#InfectiousDisease #Pulmonology

Dysregulated fibrinolysis and plasmin activation promote the pathogenesis of osteoarthritis: buff.ly/3vZK8a1

Stanford Medicine
#Inflammation

A distinct tumor microenvironment makes anaplastic thyroid cancer more lethal but immunotherapy sensitive than papillary thyroid cancer: buff.ly/4bcNNA1

#Oncology

CETP inhibition enhances monocyte activation and bacterial clearance and reduces streptococcus pneumonia–associated mortality in mice: buff.ly/3vX9JjT

Liam Brunham UBC Medicine
#Cardiology #InfectiousDisease

Fabry disease Schwann cells release p11 to induce sensory neuron hyperactivity: buff.ly/3xSGW0n
Medical College of Wisconsin
#Neuroscience

Up next in the ASCI Scientific Sessions:

Emily Wang

'Can we achieve health equity without ending mass incarceration?'

May 10, 1-2pm ET

Moderated by Susan Cheng, MD, MMSc, MPH Cedars-Sinai Academic Medicine

Free and open to all!

Register: buff.ly/4d8VsBk

Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling: buff.ly/3JymXqf

Nicole Ward Vanderbilt Health Michigan Medicine
#Dermatology #Immunology

Phase separation of SHP2E76K promotes malignant transformation of mesenchymal stem cells by activating mitochondrial complexes: buff.ly/4df0bRO

#Oncology #StemCells

OGDH and Bcl-xL loss causes synthetic lethality in glioblastoma: buff.ly/3wd4lZK

Columbia University
#Oncology