KBBQ for the Stanford Translational Investigator Program (TIP) Cardiology fellows! 6 generations (PGY 1-6) of fellows in the house. StanfordCVFellowship StanfordMedRes Daniel Li Jimmy Zheng

So fun to get together with our Stanford Cardiology Translational Investigator Pathway (TIP) group! Amazing to see how this community of physician scientists thrive StanfordCVFellowship StanfordMedRes Stanford Department of Medicine

Jimmy Zheng describing GDMT rates across 20K hospitalizations in novel EHR dataset of national hospitals finding high discontinuation rates of inpatient GDMT #ACC24. Andrew P. Ambrosy, MD Stanford Department of Medicine

Astonishing results from the DanGer Shock Trial presented at #ACC24 and out in NEJM today. In patients with ST-elevation MI with cardiogenic shock, Impella reduced all-cause mortality (45.8% Impella vs. 58.5% control) at 180 days. Some thoughts on this ground breaking trial:

#ACC24 Jimmy Zheng presenting on diuretic strategies in national sample of ADHF. Not much has changed since ADHERE registry Andrew P. Ambrosy, MD Stanford Department of Medicine

#ACC24 Mugdha Joshi telemedicine use associated with lower GDMT rx for HFrEF ‼️ more comfort with virtual care needed + multi-d support 👩🏻‍⚕️💊 Alex Sandhu Stanford Internal Medicine Chiefs Duke Cardiology Fellows

#CircACC24 #Simpub PRO-HF Trial: Routine patient-reported outcome assessment in heart failure clinic did not lead to changes in health status at one year #AHAJournals Alex Sandhu Stanford Department of Medicine ahajournals.org/doi/10.1161/CI…

#ACC24 Alex Sandhu on the main stage presenting impact of routine KCCQ assessment on ☠️, 🏥, and 💊 at 1 year. Herculean effort 🔥 John Spertus Neil Kalwani Stanford Department of Medicine

#ACC24 Sulaiman Somani on Engage stage on #AI analysis of public perceptions on CAC on social media. 😐 to ☹️ sentiment from #Reddit‼️ Fatima Rodriguez Stanford Department of Medicine Stanford Internal Medicine Chiefs

Not much has changed in AHF 🏨 weight change in the >2 decades since first reported in ADHERE Contemporary Decongestion Strategies in Patients Hospitalized for Heart Failure: A National Community-Based Cohort Study | JACC: Heart Failure jacc.org/doi/10.1016/j.… Alex Sandhu

Congrats to Jimmy Zheng on an insightful analysis showing wide variability in contemporary ADHF decongestion strategies and outcomes - an area of needed innovation in drug and device therapies Alex Sandhu Andrew P. Ambrosy, MD Ankeet S. Bhatt, MD, MBA Anu Lala-Trindade Marat Fudim, MD MHS jacc.org/doi/10.1016/j.…

Exercise may be the single most potent medical intervention ever known. Its benefits in prevention outstrip any known drugs: 50% reduction in the risk of cardiovascular disease, 50% reduction in the risk of many cancers, positive effects on mental health, pulmonary health, GI

Bold step forward in JAMA today. A viewpoint describing whether and when causal language can be used to describe the intent and results of observational studies. Led by BIDMC Smith Center and CAUSALab epidemiologist Issa Dahabreh. jamanetwork.com/journals/jama/…

#ICYMI: Results of the PRO-HF Trial Alex Sandhu Stanford Department of Medicine Neil Kalwani Jimmy Zheng

Check out PGY-1 Jimmy Zheng's publication! #ResidentResearch pubmed.ncbi.nlm.nih.gov/37004867/

HF care still limited by inadequate diuresis🚾‼️ Stanford Heart Failure, Cardiac Transplant and MCS's Alex Sandhu & Sunny Varshney, MD & colleagues show: 1⃣ - weight ⬆️in 20% of encounters 2⃣ - adjunctive 💊in < 20%, despite their efficacy Ankeet S. Bhatt, MD, MBA Steve Greene Gregg Fonarow MD Anu Lala-Trindade Marat Fudim, MD MHS pubmed.ncbi.nlm.nih.gov/38678466/

Finerenone meets primary endpoint in Phase III FINEARTS-HF🎉 ❤️ expanded treatment options for HFpEF! —> to be presented at ESC ‼️pending: the SPIRRT HFPEF trial with MRA ⁦Duke Clinical Research Institute⁩ ⁦Karolinska Institutet⁩ ⁦Uppsala University⁩ ⁦NIH NHLBI⁩ bayer.com/media/en-us/fi…

Now in JACC Journals #JACCHF Jimmy Zheng Alex Sandhu et al dive into large scale data on ADHF Diuretic Tx, 📌 Low overall weight loss (median 5lb) 📌 <20% use augmented diuretic tx What steps can be taken to implement effective practices ? 📎 tinyurl.com/msjjww8w

Substantial drop-off in GDMT use prior to hospital discharge, half without clear contraindication. Among community-based hospitals, <50% patients discharged on triple/quadruple therapy. #GDMTWorks but only if patients take them 💊 sciencedirect.com/science/articl…

Here we looked at differences in quality for HF patients hospitalized in GWTG-HF. We found quality measure performance was similar across sex, race, ethnicity, and insurance in GWTG-HF hospitals with a few notable exceptions (e.g. CRT for women).  ahajournals.org/doi/10.1161/CI…