2 weeks to go, 2 postdoc positions, 2 good to miss out! Apply by *March 27* to join our Gene Machines team at Oxford and explore transcription mechanisms in single-molecule style, in real-time, and in live cells... 🦠🧬🔬 RT RT RT please!

Our new publication by Zhaowei Liu and Edo van Veen, et al, on the acquisition and analysis of correlative optical tweezers and confocal microscopy data now out in ACS Photonics. We also made a nice online user-friendly GUI for streamlined data analysis. pubs.acs.org/doi/10.1021/ac…

Coupled or not coupled? In this preprint, we explored conditions that affect coupling (or uncoupling) between transcription, translation, and mRNA degradation in bacteria. biorxiv.org/content/10.110…

JF669 ftw! pubs.acs.org/doi/full/10.10… Tocris Bioscience Rivera-Fuentes Lab

Save the date for Single Molecule Biophysics 2025 (SMB 2025) to be held over January 5-10, 2025 (inclusive) at the Aspen Center for Physics, Aspen, Colorado. To get your name on our emailing list, contact [email protected]. Please RT. jila.colorado.edu/smb/

Our Oxford lab is hiring, we have an opening for senior technical staff (higher scientific officer) specialised in biochemistry, molecular biology, DNA replication, etc. Join us in an exciting interdisciplinary environment! Job link: my.corehr.com/pls/uoxrecruit…

Single Molecule Bacteriology III September 30 - October 3rd, 2024 in UK! Register here: eventsforce.net/biochemsoc/fro…

Abstract deadline: July 30... waiting for your latest stories!

Huge congrats to johan elf and his lab for the prestigious award and for developing this very promising technology for rapid detection of #AMR! bbc.co.uk/news/articles/…

Abstract deadline for Single Molecule Bacteriology III in the Cotswolds, UK is 30 July - just 1 mo away. eventsforce.net/biochemsoc/fro… Register early to avoid missing out! A thread on why this meeting is going to be great... 1/8

Can we tell whether a bacterial strain is sensitive or resistant to an antibiotic in 30 minutes, with a single image? Ribosome phenotypes let us see intracellular changes associated with antibiotic resistance in 1 image. #antibioticresistance doi.org/10.1101/2024.0…

New preprint! Congrats to Alison Farrar for superb work on turning "ribosome maps" into a way to detect #antibioticresistance quickly! One more fruit from our "collaborative tree" (with Christoffer Nellaker & Nicole Stoesser @ModMedMicro) planted using Oxford Martin School seeds!

Great speakers = great conference! Abstracts due July 30th... make your plans!

What a location to start collaborations in bacteriology!

Our tug-of-war paper is out! We discovered that the dynamics of the elongasome, the machinery responsible for synthesizing the sidewall of rod shaped bacteria, are regulated by molecular motor tug-of-war in B subtilis. Great work Stu Middlemiss and co! rdcu.be/dLYV0

Self-quenched fluorophores attached to short DNA labels increase signal/resolution and reduce background in DNA-PAINT and DNA-STED. We are glad that this follow-up story (more fluors) is now out in JPC. Thank you The Journal of Physical Chemistry and our great Editor Julie Biteen 🙏 Goethe-Universität

3 weeks to go... send us your single-molecule bacterial stories for our Cotswolds get-together!

A whole lotta coupling (in Pol-II txn) going on.... RNA polymerases reshape chromatin architecture and couple transcription on individual fibers: Molecular Cell cell.com/molecular-cell…