Intricate mechanism require intricate sketches! Here, we examine the way DNA is threaded around & through an SMC ring during loop extrusion and see if they fit with our roadblock data. An engaging & educational journey as we debate, revise, and refine models in the community!

As promised, stop motion of the non-topological model from the recent work by Roman Barth Biswajit Pradhan cees dekker et al.

(1/2) Our collaborative work with Camilla's group on revealing Smc5/6's role in genome organization is now available in BioRxiv: biorxiv.org/content/10.110…

Yesterday we had a wonderful group BBQ at the Max Planck Institute of Biophysics to end the summer on a high note!

A warm welcome to our first female Director Ana J. García-Sáez (Garcia Saez Lab)👏 From October, she will head the Department of Membrane Dynamics studying how the body removes damaged cells by advanced #microscopy. Max Planck Society #CellDeath #Biophysics 👉biophys.mpg.de/new-director-a…

We are very proud of our postdoc Biswajit Pradhan Biswajit Pradhan for being awarded the Marie-Sklodowska-Curie-Stipendium Hessen 2023! 🥳 Here you can see him celebrating the great news!

Warmest congrats to our postdoc Biswajit Pradhan from our Eugene Kim lab on being awarded a Marie Skłodowska-Curie Fellowship Hesse by the HMWK Hessen👏 He will study emergency repair service proteins that help to fix serious damages in our DNA. 👉biophys.mpg.de/2769107/marie-… Max Planck Society

We warmly welcome our new postdoc, Marius Rutkauskas, to the lab! He will be studying the principles of chromosomal organization using single molecule techniques 🔬 He also started preparing for halloween, after a pumpkin carving event at the Max Planck Institute of Biophysics !

#MaxPlanck Art & Science Day - for everyone interested in #science & #art! What is #autophagy? How do our cells recycle their waste? How is research communicated via art? Visit us, learn, explore, be creative! With Dorotea Fracchiolla_Art&Science, Ayelen Valko, Ariane Pessentheiner! 👉biophys.mpg.de/en/max-planck-…

Annual faculty retreat to reflect on the last year and discuss future plans: 3 intensive & insightful days to analyse what we are doing well & what we can still improve, and to exchange on challenges & best-practices. Our new director Ana Garcia has joined us for the first time!

If you are attending #S3IC2023 and are interested in Single-Molecule-Microscopy and want to learn more about the mechanism and function of Smc5/6-mediated DNA loop extrusion, do not forget to attend the talk by Eugene Kim tomorrow at 10:50 am, room 607!

Congratulations, Eugene! 🥳

Congratulations to Eugene Kim (Eugene Kim) of the Max Planck Institute of Biophysics (Max Planck Institute of Biophysics), Frankfurt on being awarded a FEBS Excellence Award, which provides €100,000 in research funding! Eugene Kim lab bit.ly/FEAs2023

Check our our newest paper available Molecular Cell! Combining in vivo and in vitro analysis, we find that Smc5/6 preferentially loads and extrudes loops of transcription-induced positive supercoils, thus promotes local cis-interactions. sciencedirect.com/science/articl…

(1/8) I am thrilled to share the latest work from Biswajit Pradhan Amar Deep from Kevin Corbett Eugene Kim lab! biorxiv.org/content/10.110… We show that the bacterial SMC Wadjet complex cleaves plasmid DNA through loop extrusion.

Check out the beautiful coverpage of our paper Molecular Cell 😊

I am very honored to receive this year's Heinz Maier-Leibnitz Prize. All thanks to my amazing team Eugene Kim lab! The award will greatly support our continued work in understanding 3D genome organization.

It was such a great ceremony! Thank you so much again!

Are you interested in genome organizing macromolecules? Join our group for a PhD or PostDoc position! Apply now for a great opportunity to do research in an international, multi-disciplinary environment! Deadline for applications is the 31.08.24. biophys.mpg.de/open-positions