Gabriel Talaia
@gtalaia
🇵🇹 Molecular Cell Biologist, Postdoc @Shawn__Ferguson Lab, @YaleCellBio
ID: 175825668
07-08-2010 18:40:06
35 Tweet
102 Followers
274 Following
New work from Swathi Devireddy, a fantastic postdoc in my lab, showing an new mechanism controlling ER exit of progranulin and prosaposin. Important for secretory pathway, lysosomes and GRN-linked frontotemporal dementia. Bluefield Project biorxiv.org/content/10.110…
Happy to celebrate and share this new paper led by Swetha Gowrishankar in collaboration with De Camilli Lab and Yale Cell Biology colleagues on roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons | Molecular Biology of the Cell molbiolcell.org/doi/10.1091/mb…
What a great experience to publish in J Cell Science. If you are interested check out the final version of the manuscript and a first author interview. journals.biologists.com/jcs/article/13… journals.biologists.com/jcs/article/13…
Check out our 'First persons' interview with Cláudia Barata-Antunes and Gabriel Talaia Gabriel Talaia on their joint project Universidade Minho investigating trafficking of the en1 carboxylate transporter: ow.ly/anS850Ju8Ui
Here is our preprint that defines a new regulatory mechanism for mTORC1 at lysosomes. Led by Gabriel Talaia with contributions from Amanda Bentley-DeSousa. Yale Cell Biology biorxiv.org/content/10.110…
Lipid transfer from the ER by Vps13 proteins is a key part of the cellular response to lysosome damage - see new work from De Camilli Lab in collab with Shawn Ferguson: biorxiv.org/content/10.110…
Thrilled to see this work finally published The EMBO Journal thanks everyone Amanda Bentley-DeSousa Shawn Ferguson Yale Cell Biology Yale Neuroscience Lysosomal TBK1 responds to amino acid availability to relieve Rab7-dependent mTORC1 inhibition | The EMBO Journal embopress.org/doi/full/10.10…
Congratulations to Gabriel Talaia and Amanda Bentley-DeSousa! I am happy to share our new study that identifies an amino acid regulated lysosomal pool of TBK1 that phosphorylates Rab7 and supports mTORC1 activation. doi.org/10.1038/s44318…
New research from Gabriel Talaia Amanda Bentley-DeSousa & Shawn Ferguson highlights a role for TANK-binding kinase 1 (TBK1) in lysosome homeostasis (alleviating Rab7-mediated inhibition of mTORC1 activation); May contribute to the pathogenesis of ALS-FTD embopress.org/doi/full/10.10…
Critical new insight into a role for TBK1 - an ALS-FTD disease gene - at lysosomes. Congrats to Gabriel Talaia Amanda Bentley-DeSousa from Shawn Ferguson lab! embopress.org/doi/full/10.10…
Lysosomal TBK1 responds to amino acid availability at the lysosome surface, to promote mTORC1 activation by relieving Rab7-dependent inhibition Gabriel Talaia Gabriel Talaia, Amanda Bentley-DeSousa Amanda Bentley-DeSousa, Shawn Ferguson Shawn Ferguson Yale Cell Biology embopress.org/doi/full/10.10…