“The papers leading to my 2016 Lasker prize were published more than 10y ago. Most would be considered quaint, preliminary and barely publishable today. One would today be criticized for failing to include a mechanism and animal experiments” nature⁩ nature.com/articles/54538…

I'm thrilled to join Dana-Farber Cancer Biology Department and Harvard Med Cell Bio as a tenure track assistant professor Sept 2024! The Gu lab elucidates mechanisms underlying cellular homeostasis, with our initial effort on nuclear protein turnover by the ubiquitin-independent midnolin-proteasome pathway

Xin is such a wonderful person and scientist - cannot recommend more!

Very nice and important paper!

Thrilled to be aboard!

Seventeen distinguished scientists have been named 2024 ASCB Fellows! This honor is given by peers to ASCB members. The new cohort will be recognized at Cell Bio 2024 in San Diego. For more details, visit: ascb.org/society-news/s…

A fun learning experience through working on this review article. The interactions between bacteria and host organelles unfolds at various levels.

And it’s out! Our lab’s very first paper is published today Nature Methods! Our calcium-activated split-TurboID (CaST) can biochemically tag activated neurons within 10 minutes, enabling a molecular handle on functionally relevant cell ensembles: tinyurl.com/ddyecxze

Sincere gratitude to all reviewers' and editorial staffs' time and efforts for making our manuscript better!!

Excited to share Deep-STARmap and Deep-RIBOmap! We enabled spatial transcriptomic and translatomic mapping of >1K genes in 200 µm thick tissue and neuron morphology co-profiling. Thanks Xiao Wang for unwavering support; Jennifer for human skin study! biorxiv.org/content/10.110…

In a new Comment, Eric Betzig describes his vision for the future of bioimaging and bioimage analysis. He further recommends "Cell Observatories" as a path forward for addressing complex outstanding biological questions. Eric Betzig nature.com/articles/s4159…

Thrilled to share our new paper just out in Science Magazine, led by the amazing postdoc Naoyuki Matsumoto! We found how patterns of spontaneous activity instruct fine-scale refinement of axonal connectivity. A great collaboration with the Crair group! science.org/doi/10.1126/sc…

Interested in connectomics or in C. elegans biology? Sharing lab's recent work on Neuroscan.net, an online open-source platform that bridges graph analytics from data science with the underlying cell biological features in the connectome. I explain how it works here 1/

Decoding the language of cells with the power of proteomics HHMI | Janelia janelia.org/news/decoding-…

🔓Decoding the language of cells with the power of proteomics.🧪 ✨New research from Janelia Group Leader Jiefu Li (Jiefu Li) & colleagues at @hhmijanelia @hhminews @stanford Broad Institute. janelia.org/news/decoding-…

In the latest issue! Molecular and cellular mechanisms of teneurin signaling in synaptic partner matching dlvr.it/TCvXBT

the lab is 2-year-old. celebrating together with our neighbor Shaohe Wang Lab ⛳️