Review| Banning and colleagues summarize diagnostic techniques, current and emerging interventions for the treatment of #microvascular dysfunction @Memfietzoglou, Giovanni Luigi De Maria Dimitrios Terentes-Printzios Rafail Kotronias MarinF Claudio Montalto nature.com/articles/s4416… 👉rdcu.be/cLzIU

Excellent discussion of the AltShock-2 trial testing early IABP use in ADHF; the MYTHS trial exploring steroids in acute myocarditis; and the STEMI #DTU Trial in Milan. All three testing early interventions for SCAI Now Shock A-B patients. Great to see #CSWG impacting minds globally

Such a great pleasure to participate di the #stemidtu trial with ASST Ospedale Niguarda This is the first in-person meeting after covid. Looking forward to improve patients care and to contribute to a new paradigm shift in #stemi w/ chief Abiomed

Evolution of STEMI treatment from door-to-balloon to door-to-unload in the STEMI DTU RCT. Tremendous energy at the enrolling sites 24/7 to complete this landmark study, and with unparalleled leadership from the PI’s. Exciting Investigator Summit! William W. O'Neill Navin Kapur

#Statistics thought of the day:It is not appropriate to compute a mean or run parametric regression on % change unless you first compute log(% change/100 + 1) to undo damage done by % change fharrell.com/post/percent #statstwitter Vanderbilt Department of Biostatistics Vanderbilt University Data Science Institute #StatThink #bbrcourse

What is the optimal regimen for #P2Y12 antagonism in #elderly with ACS? A network meta-analysis of RCTs on #ehjcvp provides novel insights 💊⤵️ academic.oup.com/ehjcvp/article… #CardioTwitter #Cardiology Stefan Agewall Claudio Montalto Gabriele Crimi, MD. Italo Porto Azeem Latib antonio mangieri

This is the 1st🥇meta-analysis specifically evaluating the impact of DAPT #duration after PCI in pts with an indication for OAC - irrespective of OAC #type❗ New data in #ehjcvp supports periprocedural #triple therapy💊⤵️ academic.oup.com/ehjcvp/advance… Marco Valgimigli Claudio Montalto Stefan Agewall

Our meta-analysis (5RCT-7665pts) evaluating specifically DAPT duration after PCI in pts on long-term OAC (similar OACtype & indication) Periproc/Abbrev DAPT ⬇️bleeding 🟰MACE Davide Capodanno Claudio Montalto vranckx pascal antonio micari @RenatoDLopes1 Marco Valgimigli PCRonline 🫀 European Society of Cardiology Journals

Latest results of our meta-analysis focused on #HBR pts undergoing #PCI 🛠️ Abbreviated(1-3m) vs. standard #DAPT (≥6m) 🔸⬇️🩸 24% MCRB & 20% major bleed 🔸⬇️☠️ 21% CV Death 🔸🟰 MACE (irrespective ACS vs. CCS) Full paper European Society of Cardiology Journals->shorturl.at/cpvW0 European Society of Cardiology EHJ Editor-in-Chief

📣This week #JournalClub discusses #DAPT duration post #PCI in #HBR & #OAC pat @ESCJournals #EHJ ⭐️Expert Prof. Marco Valgimigli & presenters Claudio Montalto + Francesco Costa 🗓Time: Wed Feb 22nd, 6pm(CET) ➡️DM 4 ZOOM🔗 As a starter s. #BackgroundSession w/🔑literature: linktr.ee/thecardiojc

⭐️Tomorrow at 6️⃣pm CET the #CardioJournalClub is live ➡️Join Prof. Marco Valgimigli & the presenters Claudio Montalto + Francesco Costa who will discuss 2 @ESCJournals papers on #DAPT duration post #PCI in #HBR & #OAC pat 🗓Wed 22nd Feb ⏰6.00 pm (Rome) ➡️DM for ZOOM link🔗

One of the most used definition for Complex PCI in studies and meta-analysis was proposed by Gennaro Giustino, MD chief Antonio Colombo in this paper published on @JACC Demonstrating that Complex PCI benefit from longer DAPT duration jacc.org/doi/abs/10.101…

Dual antiplatelet therapy duration after percutaneous coronary intervention in high bleeding risk: new meta-analysis in current EHJ issue. #DAPT #platelets #PCI #cardiotwitter European Society of Cardiology Journals European Society of Cardiology

Ok this is big. Web of Science just removed the MDPI flagship journal IJERPH from their lists. This means IJERPH has no more an Impact Factor. Why is this big? What are the implications? 🧵