Online now! Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer dlvr.it/TD1T1N

Online now! Years of endurance exercise training remodel abdominal subcutaneous adipose tissue in adults with overweight or obesity dlvr.it/TD3MWx

Online now! Long-term exercise training has positive effects on adipose tissue in overweight or obesity dlvr.it/TD3MXb

NEWS&VIEWS | Paolicelli & Pluchino (Cambridge University) Two studies in Nature Metabolism demonstrate that impairing the mitochondrial respiratory chain, via deficiencies in complex I or complex III, affects #microglia in a highly context-dependent manner. nature.com/articles/s4225…

Online now! Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency dlvr.it/TD645r

Online now! O-GlcNAc transferase regulates glycolytic metabolon formation on mitochondria to enhance ATP production dlvr.it/TD647T

Featured in our October issue: Emma Börgeson, Saeideh Tavajoh, Stephan Lange & Niels Jessen discuss the advantages and disadvantages of different methods of assessing #adiposity in clinical settings rdcu.be/dTKXj

From our October issue: a News & Views from Yusman Manchanda & Alejandra Tomas on new insights into the regulation of #GIPR signalling (£) go.nature.com/3XwRHQf

From our October issue: Didier Hober and colleagues review the relationship between SARS-CoV-2 infection and type 1 #diabetes mellitus (£) go.nature.com/3zrnFne @debuycyr1994

NEWS&VIEWS | Richard Possemato (NYU Grossman School of Medicine) Resistance to glutamine restriction is mediated by increased serine synthesis. The high affinity of serine synthesis enzyme PSAT1 for glutamate drives sustained glutamine utilization. nature.com/articles/s4225…

A study in Nature Aging shows that the ‘weekend warrior’ physical activity pattern, with concentrated exercise over one to two days, is similarly linked to lower risk of brain disorders compared to regular exercise. 🔒 go.nature.com/46ZZOYP

REVIEW | Cătălina Cuparencu et al. (University of Copenhagen) Here is an update on the most useful #biomarkers for assessing food intake, which could help accelerate the application of biomarkers of food intake for improving human nutritional #research #diet 🍽️ nature.com/articles/s4225…

NEWS&VIEWS | Zhao et al. (Rutgers University) The gut #microbiota members Desulfovibrio spp. produce hydrogen sulfide, which disrupts host metabolism by suppressing GLP-1 production in mice. nature.com/articles/s4225…

RESEARCH | Y Qiu, M Lukey et al. (@CHSL): The study provides insight into the metabolic adaptations that enable breast cancer cells to proliferate in the face of glutaminolysis blockade. #CancerResearch nature.com/articles/s4225…

Online now! Publisher Correction: Efferocytosis drives a tryptophan metabolism pathway in macrophages to promote tissue resolution dlvr.it/TDLRVp

#NatMetabPicks | In nature led by J Wang & W Wang (Shanghai Jiao Tong University): Neurons in the vagus are involved in the absorption of fat in the intestine, and the natural compound puerarin modulates this brain-gut axis to reduce fat absorption. nature.com/articles/s4158…