Philipp Mews
@philippmews
Asst Professor @BUMedicine exploring how metabolic signals influence the epigenome and brain function. Impact of diet/drugs on chromatin & behavior @buCSNneuro
ID: 870022302293004289
https://www.bumc.bu.edu/ppb/the-mews-lab/ 31-05-2017 21:00:55
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📢New paper! Very proud to share our paper in molecularpsychiatry about circulating microRNA as biomarkers and treatment for depression! Led by the brilliant (Twitter less) Yentl van der Zee, with the guidance of the all-mighty Eric J. Nestler, MD, PhD and me. rdcu.be/cSx9Z 🧵
New paper from my group! M. Gunes Kutlu Jennifer Zachry and Patrick Melugin show that novelty effects on learning are mediated by dopamine release in ways that cannot be explained by prediction-error models, but still robustly influence predictive learning
Check out our latest review where we discuss clinical & preclinical evidence to better understand how ELA shapes the brain during sensitive periods Lauren Malave Milenna van Dijk Christoph Anacker Nature Portfolio nature.com/articles/s4139…
I am incredibly proud of Orna Issler 💔 and our collaborators for this new work using integrated human-mouse investigations to understand the molecular mechanisms of sex differences in depression. This exciting discovery has inspired my very first "tweetprint". Here we go…🤞🏼
PRESS RELEASE: Philipp Mews Ashley Cunningham, MSc 🧠 Eric J. Nestler, MD, PhD, et al. find #CocaineUseDisorder alters gene networks of #Neuroinflammation and #Neurotransmission in humans - analysis reveals similar changes in the #brain’s functioning in both humans & #mousemodels👉bit.ly/3xjZNxz
Thrilled to share our latest paper in Science Signaling! Our subcellular proteomics study revealed how cocaine dynamically influences protein translocation onto and off chromatin in the nucleus accumbens. Fun project w/ Lucas Sosnick Simone Sidoli & Eric J. Nestler, MD, PhD science.org/doi/10.1126/sc…
Extremely proud to share this work with mastermind Bowen Tan and Tobias Nöbauer representing an awesome collaboration across the labs of Vaziri Lab, Jeffery Friedman, and Eric J. Nestler, MD, PhD now out in Science Magazine. science.org/doi/10.1126/sc…
Scientists at Friedman Brain Institute have decoded how cocaine use disorder skews the modification of proteins in the brain’s “pleasure center” in mice—providing a compendium of data that may inform future therapies for cocaine addiction. Eric J. Nestler, MD, PhD Philipp Mews scim.ag/6GQ