Roshni Patel
@roshniapatel
Postdoc with @DocEdge85. PhD at Stanford Genetics with @jkpritch. Pop gen, complex traits, ethics, equity. She/her. 🏳️🌈
ID: 1030847704941912066
http://roshnipatel.github.io 18-08-2018 16:03:39
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Shai Carmi Roshni Patel et al. 2024 is illuminating re: why it can be difficult to distinguish signatures of the two. biorxiv.org/content/10.110…
Excited to share my 1st-author work from the Arbel Harpak Lab! We examine the accuracy of polygenic score (PGS) predictions across individuals in the UK Biobank. We make 3 observations that expose gaps in our understanding of PGS “portability”. biorxiv.org/content/10.110… (1/28)
Relatedly, some cool recent work from Roshni Patel jeffrey spence Jonathan Pritchard et al. dives deep into expectations, based on models of natural selection, for allele frequency in a group B conditional on allele frequency in group A. biorxiv.org/content/10.110… (18/28)
We know that DNA introgressed from one population into another is often deleterious, but why? Carl Veller and I show that stabilizing selection, by itself, can induce selection against introgressed ancestry. doi.org/10.1101/2024.0…
In a new manuscript, we argue that confounding is a difficult problem to shake in studies of genetic influences on human behavior. (With John Benning, Olivia Smith (she/her), Ruth Shaw, and Arbel Harpak) biorxiv.org/content/10.110…
Really cool work from Juehan Wang and Steven Gazal providing evidence that genes differentially expressed across continental ancestries are enriched for GxE.
belated announcement that after six wonderful years with Jonathan Pritchard, I am now at USC (and very excited to be here!)
I am excited to share that I have started a postdoc at Stanford Center for Biomedical Ethics (SCBE)! I am so excited for all the new learning, collaboration, and projects ahead of me!
I would not be here today if I didn't have the chance to create the Genetics, Ethics, and Society class alongside Roshni Patel and many others. A note to grad students -- your outreach/advocacy/etc can become so much more!