1/ Hi 👋 #medtwitter #neurotwitter #neurocritcare, today we will focus on the following article in my role as #SoMeAmbassador for @neurocritcarej: x.com/NeurocritCareJ…

Humbled to have co-led this trial showing benefit of MT in early presenting pts with unlimitedly large infarcts. Large core regardless of size = poor prognosis, but not treatment effect modifier. IMAGING CANNOT IDENTIFY PTS WHO DON'T BENEFIT FROM MT !! nejm.org/doi/full/10.10…

Cool study of long-term outcomes after #ICH. With over 5 years of follow-up: mortality plateaus at 90 days but functional outcomes improve significantly between 6 and 12 months. Implications for trial design. rdcu.be/dHNwq Neurocritical Care Society Neurocritical Care

Ok my first thoughts on ANEXXA-I after my initial read of the study: The two outcomes I care deeply about are (a) ICH expansion and (b) neurologic outcome. Anti Factor Xa activity is just not a meaningful trial endpoint IMHO. 1/?

AIS patients sometimes present with a non-AFib related indication for acute anticoagulation (arterial or LV thrombus, ACS, acute DVT/PE) This study suggests that early AC (<3 days) is fine. Safe with minimal risk of intrcranial bleeding and much les risk of future thrombolic

Thank you NeurotraumaSociety for this opportunity to share our #sim #meded experiences! Swarna Rajagopalan MD MS Dan Tonetti Shivani Ghoshal Cooper Neurology Residency Cooper University Health Care CooperNeuroSurg Columbia Neurology Residency Temple Neurology Lewis Katz School of Medicine

Thank you Neurocritical Care Society for introducing us over a decade ago at an annual meeting, we've come a long way! Thank you NeurotraumaSociety for the wonderful opportunity! Lauren Koffman DO, MS

1/ A woman presents after a v fib cardiac arrest, ROSC achieved at 30 mins. She has been comatose for 2 days. No sedation. Fever prevention has been achieved. 36 hours after arrest, she develops generalized myoclonus. This is a dismal prognostic sign… right? Image: PM 27351833

If you intubate you need to read the #PREOXI trial! -n=1301 people requiring intubation in ED/ ICU were randomized to preoxygenation with oxygen mask vs non-invasive ventilation (NIV) -NIV HALVED the risk of hypoxemia: 9 vs 18% -NIV reduced mortality: 0.2% vs 1.1% #CCR24 🧵 1/

Muehlschlegel et al: Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury Link: ow.ly/SnEw50Rk8Ue Neurocritical Care Society @buslkatharina @smuehlschMD

Takara et al: Association Between Early Mobilization and Functional Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage: A Multicenter Retrospective Propensity Score-Matched Study Link: ow.ly/3c3y50RoAvB Neurocritical Care Society #NeuroCritCare

Intra‐arterial Selective Bevacizumab Administration in the Middle Meningeal Artery for Chronic Subdural Hematoma: An Early Experience in 12 Hemispheres | Stroke: Vascular and Interventional Neurology ahajournals.org/doi/10.1161/SV…

In poorly responsive or unresponsive patients, can automated pupillometry identify covert consciousness? Daniel Kondziella Neurocritical Care #infographic #criticalcare #neurocriticalcare #icu Aarti Sarwal, FNCS, FAAN, FCCM, RPNI, Professor Richard Choi, DO, FNCS Casey Albin, MD

How many patients with severe brain injuries have we examined who appeared unresponsive, and we assumed they were unconscious? International James S. McDonnell Foundation study in NEJM suggests that 25% were covertly conscious: nejm.org/doi/full/10.10… Profound clinical & ethical implications...

Covert Consciousness in the ICU A review in collaboration with David Menon Thank you Critical Care Medicine for highlighting this topic, now even more relevant after yesterday's NEJM paper (nejm.org/doi/full/10.10…) journals.lww.com/ccmjournal/abs… MGH Neurocritical Care MassGeneralNeuroscience MGH Neurology

(1/x) Intubating critically ill patients in the ICU has some important differences to the ED or OR. It also carries with it a 3% chance of cardiac arrest. Yes, THREE percent (PMID: 33755076) This may be the highest risk procedure we perform in the ICU. Here is how you can make

Important study by jan claassen and group from Columbia NeuroCriticalCare. EEG-based motor command paradigms are limited in their ability to detect cognitive-motor dissociation in pts with aphasia: Non-language based stimuli are required. Neurocritical Care rdcu.be/dR2PN

Let's learn something new about ABG. We all know & use the Boston Approach to ABG, it's relatively simple and commonly used. Let's learn something about technically more sound but lesser used approach to ABG, Stewart Approach. My first #MedEd thread, please share maximum. 📝

Another super cool graphic! 😎😎😎

Please join Aarti Sarwal, FNCS, FAAN, FCCM, RPNI, Professor Golda Boahene-Nartey and myself today on this neuromonitoring webinar discussing basics and tips/ tricks of bedside neuromonitoring! 2pm CST/ 3pm EST